Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R31 | P59538 | 2/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | XDH | P47989 | 2/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14421486 | 0.93 | TAS2R31 (0.57) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| SCHEMBL16894619 | 0.90 | CYP19A1 (0.50) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| SCHEMBL30873340 | 0.90 | CYP19A1 (0.50) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| SCHEMBL31065850 | 0.90 | CYP19A1 (0.50) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| SCHEMBL15462191 | 0.89 | CYP19A1 (0.54) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| SCHEMBL19736058 | 0.88 | ODC1 (0.49) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| SCHEMBL12878874 | 0.85 | CYP19A1 (0.65) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| SCHEMBL30912310 | 0.84 | ABCG2 (0.58) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| SCHEMBL16894644 | 0.84 | ABCG2 (0.58) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| SCHEMBL16894655 | 0.84 | CYP1A1 (0.60) | TAS2R31CYP19A1CYP3A4CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669003-B2 | Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs | JIN YONGRI (CN) | 2017-06-06 | — | — | US | claimed |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | JIN YONGRI (CN) | 2015-07-16 | — | — | US | claimed |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | WLLGEN, INC. (US) | 2014-02-06 | — | — | US | claimed |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | WELLGEN, INC. | 2007-11-29 | — | — | US | claimed |
| US-9669003-B2 | Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs | JIN YONGRI (CN) | 2017-06-06 | — | — | US | disclosed |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | JIN YONGRI (CN) | 2015-07-16 | — | — | US | disclosed |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | WLLGEN, INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | WLLGEN, INC. (US) | 2014-02-06 | — | — | US | disclosed |
| EP-2010194-A2 | HYDROXYLATED POLYMETHOXYFLAVONE COMPOSITIONS | Rutgers, The State University of New Jersey (US) | 2009-01-07 | — | — | EP | disclosed |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | WELLGEN, INC. | 2007-11-29 | — | — | US | disclosed |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | WELLGEN, INC. | 2007-11-29 | — | — | US | disclosed |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | WELLGEN, INC. | 2007-11-29 | — | — | US | disclosed |
| WO-2007109071-A2 | HYDROXYLATED POLYMETHOXYFLAVONE COMPOSITIONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2007-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | PLIN5, FANCF, COXFA4 | TAS2R31 3899/4885CYP19A1 11/4885TP53 984/4885 |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | CYP2D6, GATAD2A, CYP3A43 | TAS2R31 1825/4885CYP19A1 1387/4885TP53 4877/4885 |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | PLIN5, FANCF, COXFA4 | TAS2R31 3899/4885CYP19A1 11/4885TP53 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.