SCHEMBL4129634

SCHEMBL4129634

CC(I)CCC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4674604 0.86 ALOX15 (0.30)
SCHEMBL1471676 0.75
SCHEMBL26081754 0.73 LMNA (0.33)
SCHEMBL669083 0.73
SCHEMBL14293684 0.73
SCHEMBL11364332 0.71
SCHEMBL4976367 0.71
SCHEMBL135577 0.71
Ammonia Solution, Strong SCHEMBL20531957 0.71 LMNA (0.32)
SCHEMBL1678170 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090186941-A1 ORGANIC SULFUR COMPOUNDS AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-23 US disclosed
CN-101312944-A Organic sulfur compounds and their use as arthropodicides SUMITOMO CHEMICAL CO (JP) 2008-11-26 CN disclosed
EP-1951664-A1 ORGANIC SULFUR COMPOUNDS AND USE THEREOF AS ARTHROPODICIDES Sumitomo Chemical Company, Limited (JP) 2008-08-06 EP disclosed
WO-2007060839-A1 ORGANIC SULFUR COMPOUNDS AND USE THEREOF AS ARTHROPODICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-31 WO disclosed
EP-1403238-B1 PROCESS FOR PRODUCING FLUORINATED ALCOHOL TOSOH F TECH INC (JP) 2007-04-04 EP disclosed
US-7119203-B2 Piperidinyl- and piperazinyl-sulfonylmethyl hydroxamic acids and their use as protease inhibitors PHARMACIA CORPORATION (US) 2006-10-10 US disclosed
EP-1689743-A2 PIPERIDINYL-AND PIPERAZINYL-SULFONYLMETHYL HYDROXAMIC ACIDS AND THEIR USE AS PROTEASE INHIBITORS Pharmacia Corporation (US) 2006-08-16 EP disclosed
US-20050209278-A1 Piperidinyl- and piperazinyl-sulfonylmethyl hydroxamic acids and their use as protease inhibitors PHARMACIA CORPORATION 2005-09-22 US disclosed
US-6894197-B2 Reacting 4,4,4-trifluorobutylhalides with potassium salt of 4-hydroxybutyrate in gamma-butyrolactone solvents to form 4,4,4-trifluorobutanol; hydrolysis TOSOH F-TECH, INC. (JP) 2005-05-17 US disclosed
WO-2005042521-A2 PIPERIDINYL-AND PIPERAZINYL-SULFONYLMETHYL HYDROXAMIC ACIDS AND THEIR USE AS PROTEASE INHIBITORS PHARMACIA CORPORATION (US) 2005-05-12 WO disclosed
EP-1501827-A2 PIPERIDINYL-AND PIPERAZINYL-SULFONYLMETHYL HYDROXAMIC ACID AND THEIR USE AS PROTEASE INHIBITORS Pharmacia Corporation (US) 2005-02-02 EP disclosed
US-20050009838-A1 Piperidinyl-and piperazinyl-sulfonylmethyl hydroxamic acids and their use as protease inhibitors PHARMACIA CORPORATION 2005-01-13 US disclosed
US-20040152926-A1 Process for producing fluorinated alcohol TOSOH F-TECH INC. (JP) 2004-08-05 US disclosed
EP-1403238-A1 PROCESS FOR PRODUCING FLUORINATED ALCOHOL Tosoh F-Tech, Inc. (JP) 2004-03-31 EP disclosed
WO-2003091247-A2 PIPERIDINYL-AND PIPERAZINYL-SULFONYLMETHYL HYDROXAMIC ACIDS AND THEIR USE AS PROTEASE INHIBITORS PHARMACIA CORPORATION (US) 2003-11-06 WO disclosed
US-5436260-A Substituted 1-benzylimidazole-5-methylidene hydantoins WARNER-LAMBERT COMPANY (US) 1995-07-25 US disclosed
US-5308853-A Hypotensive agents, antagonists of angiotensin II WARNER-LAMBERT COMPANY (US) 1994-05-03 US disclosed
WO-1993013077-A1 ANGIOTENSIN II RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1993-07-08 WO disclosed
EP-0252736-B1 PROCESS FOR PREPARING FLUORINE-CONTAINING CARBOXYLIC ACID ESTER SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-07-24 EP disclosed
EP-0252736-A2 Process for preparing fluorine-containing carboxylic acid ester SAGAMI CHEMICAL RESEARCH CENTER (JP) 1988-01-13 EP disclosed