Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3A | Q9Y6K1 | 3/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.42 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13850602 | 0.89 | DNMT3A (0.49) | DNMT3AMCHR1HDAC3HDAC1HDAC2 | |
| SCHEMBL4129696 | 0.89 | DNMT3A (0.44) | DNMT3AMCHR1HDAC3HDAC1HDAC2 | |
| SCHEMBL4724035 | 0.87 | DNMT3A (0.47) | DNMT3AMCHR1HDAC3HDAC1HDAC2 | |
| SCHEMBL4722646 | 0.87 | DNMT3A (0.46) | DNMT3AMCHR1HDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL4122777 | 0.87 | DNMT3A (0.46) | DNMT3AMCHR1HDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL4122709 | 0.86 | DNMT3A (0.46) | DNMT3AMCHR1HDAC3HDAC1HDAC2 | |
| SCHEMBL4116963 | 0.85 | DNMT3A (0.60) | DNMT3AMCHR1HDAC3HDAC1HDAC2 | |
| SCHEMBL4764473 | 0.85 | DNMT3A (0.46) | DNMT3AMCHR1HDAC3HDAC1HDAC2 | |
| SCHEMBL13850599 | 0.85 | DNMT3A (0.47) | DNMT3AMCHR1HDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL4122544 | 0.84 | DNMT3A (0.46) | DNMT3AMCHR1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124624-A1 | SUBSTITUTED 1-AMINOPHTHALAZINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2009-05-14 | — | — | US | disclosed |
| US-20090124624-A1 | SUBSTITUTED 1-AMINOPHTHALAZINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124624-A1 | SUBSTITUTED 1-AMINOPHTHALAZINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF | AGTR1, AGTR2, AHR | DNMT3A 3277/4885MCHR1 138/4885HDAC3 518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.