Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941764 | 0.93 | MAPT (0.52) | HTR4ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL3944471 | 0.93 | MAPT (0.52) | HTR4ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL3943996 | 0.93 | MAPT (0.52) | HTR4ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL3941856 | 0.93 | MAPT (0.52) | HTR4ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL3942598 | 0.93 | MAPT (0.52) | HTR4ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL4542623 | 0.92 | MAPT (0.52) | HTR4ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL3951135 | 0.89 | MAPT (0.49) | HTR4ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL4029173 | 0.88 | MAPT (0.47) | HTR4ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL4347407 | 0.88 | ALDH1A1 (0.40) | ALDH1A1KDM4ETSHRMAPTL3MBTL1 | |
| SCHEMBL3944346 | 0.88 | MAPT (0.49) | HTR4ALDH1A1KDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | claimed |