Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944471 | 0.88 | MAPT (0.52) | ALDH1A1KDM4EHSD17B10GAARAB9A | |
| SCHEMBL3943996 | 0.88 | MAPT (0.52) | ALDH1A1KDM4EHSD17B10GAARAB9A | |
| SCHEMBL3941856 | 0.88 | MAPT (0.52) | ALDH1A1KDM4EHSD17B10GAARAB9A | |
| SCHEMBL3942598 | 0.88 | MAPT (0.52) | ALDH1A1KDM4EHSD17B10GAARAB9A | |
| SCHEMBL4130491 | 0.88 | HTR4 (0.49) | ALDH1A1KDM4EPOLBTSHRNPSR1 | |
| SCHEMBL3941764 | 0.88 | MAPT (0.52) | ALDH1A1KDM4EHSD17B10GAARAB9A | |
| SCHEMBL4542623 | 0.86 | MAPT (0.52) | ALDH1A1KDM4EHSD17B10GAARAB9A | |
| SCHEMBL4032664 | 0.85 | RAB9A (0.42) | ALDH1A1KDM4EPOLBRAB9ANPC1 | |
| SCHEMBL3943591 | 0.85 | RAB9A (0.39) | ALDH1A1KDM4EHPGDTSHRRAB9A | |
| SCHEMBL3945834 | 0.84 | RAB9A (0.38) | ALDH1A1KDM4EHPGDMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |