⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1201233 | 0.83 | NPC1 (0.51) | — | |
| SCHEMBL5684870 | 0.83 | NPC1 (0.51) | — | |
| SCHEMBL27864324 | 0.83 | NPC1 (0.51) | — | |
| SCHEMBL4440609 | 0.82 | NPC1 (0.57) | — | |
| Hydrochloric Acid SCHEMBL5447489 | 0.82 | NPC1 (0.50) | — | |
| SCHEMBL18884424 | 0.82 | AOC3 (0.50) | — | |
| SCHEMBL22593395 | 0.81 | NPC1 (0.45) | — | |
| SCHEMBL5246407 | 0.80 | — | — | |
| SCHEMBL5245778 | 0.80 | — | — | |
| SCHEMBL2251571 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005848-B1 | N-ALKYLATED AMINOALCOHOLS AND THEIR SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1981-12-30 | — | — | EP | claimed |
| JP-1083079-A | — | — | None | — | — | JP | disclosed |
| US-8957205-B2 | Cycloalkane carboxamide derivatives and production process of same | SEIKAGAKU CORPORATION (JP) | 2015-02-17 | — | — | US | disclosed |
| US-20090156805-A1 | Cycloalkane Carboxamide Derivatives and Production Process of Same | SEIKAGAKU CORPORATION (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1972615-A1 | CYCLOALKANECARBOXAMIDE DERIVATIVE AND METHOD FOR PRODUCING SAME | SEIKAGAKU CORPORATION (JP) | 2008-09-24 | — | — | EP | disclosed |
| EP-1765817-A1 | THIAZOLINONE UNSUBSTITUTED QUINOLINES | F.HOFFMANN-LA ROCHE AG (CH) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006002829-A1 | THIAZOLINONE UNSUBSTITUTED QUINOLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-01-12 | — | — | WO | disclosed |
| US-20050049245-A1 | Heteroaryl-ethanolamine derivatives as antiviral agents | PHARMACIA & UPJOHN COMPANY | 2005-03-03 | — | — | US | disclosed |
| WO-2004106345-A2 | HETEROARYL-ETHANOLAMINE DERIVATIVES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2004-12-09 | — | — | WO | disclosed |
| US-5939398-A | ANTIATHEROSCLEROSIS AGENTS | PFIZER INC. (US) | 1999-08-17 | — | — | US | disclosed |
| EP-0161801-B1 | PERHYDROTHIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANKYO COMPANY LIMITED (JP) | 1990-11-07 | — | — | EP | disclosed |
| EP-0365045-A1 | Perhydrothiazepine derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1990-04-25 | — | — | EP | disclosed |
| EP-0304409-A1 | 5-Heterocyclic-substituted oxazolidine haloacetamides | MONSANTO COMPANY (US) | 1989-02-22 | — | — | EP | disclosed |
| US-4699905-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1987-10-13 | — | — | US | disclosed |
| EP-0161801-A2 | Perhydrothiazepine derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1985-11-21 | — | — | EP | disclosed |
| US-4460580-A | N-Alkylated aminoalcohols and their pharmaceutical compositions useful for the treatment of cardiac insufficiency | CIBA-GEIGY CORPORATION (US) | 1984-07-17 | — | — | US | disclosed |
| US-4105663-A | HYPOTENSIVE, BLOCKING AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-08-08 | — | — | US | disclosed |
| US-4093628-A | HYPOTENSIVE AGENTS, BLOCKING AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4082772-A | HYPOTENSIVE AGENTS, B-ADRENERGIC BLOCKING AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |
| US-4024156-A | Thiophene ethanolamines | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |