Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4135595 | 0.91 | KMT2A (0.44) | KMT2AGAAHSD17B10PRMT5MEN1 | |
| SCHEMBL4129127 | 0.86 | PRKD1 (0.46) | KMT2AGAASMN1; SMN2MEN1MCHR1 | |
| Formaldehyde SCHEMBL4135580 | 0.84 | PRKD1 (0.45) | GAASMN1; SMN2MCHR1ERN1 | |
| SCHEMBL4136188 | 0.83 | MAPK14 (0.50) | KMT2ASMN1; SMN2MEN1L3MBTL1MAPK14 | |
| SCHEMBL4128788 | 0.82 | HRH3 (0.49) | MCHR1L3MBTL3L3MBTL1FAAH | |
| SCHEMBL4133418 | 0.81 | L3MBTL3 (0.51) | KMT2AGAAHSD17B10MEN1MCHR1 | |
| SCHEMBL4144270 | 0.80 | TDP2 (0.45) | L3MBTL3L3MBTL1FAAHERN1 | |
| SCHEMBL4140115 | 0.80 | TDP2 (0.45) | L3MBTL3L3MBTL1FAAHERN1 | |
| SCHEMBL4140118 | 0.80 | TDP2 (0.45) | L3MBTL3L3MBTL1FAAHERN1 | |
| SCHEMBL4136371 | 0.80 | HRH3 (0.52) | SMN1; SMN2MCHR1L3MBTL3L3MBTL1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163482-A1 | TETRALINES ANTAGONISTS OF THE H-3 RECEPTOR | MCHARDY STANTON FURST | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163482-A1 | TETRALINES ANTAGONISTS OF THE H-3 RECEPTOR | HRH3, HRH4, HRH1 | KMT2A 1670/4885GAA 294/4885HSD17B10 1285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.