Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 8/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.46 |
| ▸ | CDK1 | P06493 | 8/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 2/20 | 0.36 |
| ▸ | CLK2 | P49760 | 2/20 | 0.36 |
| ▸ | CDK7 | P50613 | 2/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.36 |
| ▸ | NT5E | P21589 | 3/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238901 | 0.93 | CDK2 (0.38) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL4123532 | 0.90 | CCNE1 (0.36) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL1412174 | 0.88 | ADORA3 (0.42) | NT5EADORA3ADORA1 | |
| SCHEMBL4127536 | 0.88 | CCNE1 (0.51) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL4111357 | 0.85 | CCNE2 (0.38) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| Trifluoroacetic Acid SCHEMBL4131725 | 0.85 | CCNE1 (0.48) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL1402144 | 0.84 | ADORA3 (0.42) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL4125024 | 0.81 | ADORA2A (0.40) | CDK2CCNE1CDK1ADORA3ADORA1 | |
| SCHEMBL4111505 | 0.81 | ADORA2A (0.42) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL4124600 | 0.81 | CCNE2 (0.37) | CDK2CCNE1CCNE2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099214-A1 | Organic Compounds | NOVARTIS AG | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099214-A1 | Organic Compounds | CYP3A43, OXER1, OPRM1 | CDK2 886/4885CCNE1 267/4885CCNE2 444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.