SCHEMBL413179

SCHEMBL413179

NCCCC[C@H](NC(=O)C(CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)CN)C(=O)Nc1ccc2ccccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 2/20 0.46
▸ CALCRL Q16602 1/20 0.46
▸ CTNNB1 P35222 7/20 0.44
▸ EPHX1 P07099 1/20 0.43
▸ PLG P00747 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ HDAC1 Q13547 2/20 0.42
▸ LTA4H P09960 1/20 0.42
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ HIF1A Q16665 1/20 0.42
▸ SLC15A2 Q16348 1/20 0.42
▸ ROCK2 O75116 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9489894 0.92 MEN1 (0.49) CYP1A2CALCRLPLGGAARAB9A
SCHEMBL2377610 0.84 CCKBR (0.45) SLC15A2ROCK2
SCHEMBL18787564 0.79 SSTR3 (0.54) CALCRLLTA4HSSTR3
SCHEMBL7850346 0.78 LTA4H (0.54) CALCRLLTA4HROCK2
SCHEMBL8342382 0.77 MEN1 (0.43) CYP1A2EPHX1GAARAB9ASMN1; SMN2
SCHEMBL17329292 0.77 KDM1A (0.58) CYP1A2GAARAB9ASMN1; SMN2HDAC1
SCHEMBL29802269 0.77 KDM1A (0.58) CYP1A2GAARAB9ASMN1; SMN2HDAC1
SCHEMBL3103486 0.77 KDM1A (0.58) CYP1A2GAARAB9ASMN1; SMN2HDAC1
SCHEMBL29574640 0.77 SLC15A2 (0.57) CALCRLSLC15A2
SCHEMBL7859203 0.76 LTA4H (0.55) CALCRLSMN1; SMN2LTA4HSSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3184640-A2 PROTEIN BODY-INDUCING POLYPEPTIDE SEQUENCES Zera Intein Protein Solutions, S.L. (ES) 2017-06-28 — — EP disclosed
US-9637751-B2 Recombinant protein body-inducing polypeptides ERA BIOTECH, S.A. (ES) 2017-05-02 — — US disclosed
EP-2576797-B1 PROTEIN BODY-INDUCING POLYPEPTIDE SEQUENCES ZERA INTEIN PROTEIN SOLUTIONS S L (ES) 2017-01-25 — — EP disclosed
US-20150335720-A1 PRODUCTION OF BIOLOGICALLY ACTIVE PROTEINS ERA BIOTECH SA (ES) 2015-11-26 — — US disclosed
CN-101415820-B Production of biologically active proteins ERA BIOTECH S L 2013-08-07 — — CN disclosed
EP-2576797-A1 PROTEIN BODY-INDUCING POLYPEPTIDE SEQUENCES ERA Biotech, S.A. (ES) 2013-04-10 — — EP disclosed
US-8163880-B2 Production of biologically active proteins ERA BIOTECH S.A. (ES) 2012-04-24 — — US disclosed
EP-1994145-B1 PRODUCTION OF BIOLOGICALLY ACTIVE PROTEINS ERA BIOTECH SA (ES) 2012-04-04 — — EP disclosed
EP-2418284-A1 Protein body-inducing polypeptide sequences ERA Biotech, S.A. (ES) 2012-02-15 — — EP disclosed
US-20120020992-A1 Production of Biologically Active Proteins ERA BIOTECH, S.A. (ES) 2012-01-26 — — US disclosed
US-20110305718-A1 Recombinant Protein Body-Inducing Polypeptides ERA BIOTECH S.A. 2011-12-15 — — US disclosed
WO-2011147995-A1 PROTEIN BODY-INDUCING POLYPEPTIDE SEQUENCES ERA BIOTECH, S.A. (ES) 2011-12-01 — — WO disclosed
EP-2351834-A2 Production of biologically active proteins ERA Biotech, S.A. (ES) 2011-08-03 — — EP disclosed
CN-101415820-A Production of biologically active proteins ERA BIOTECH SA (ES) 2009-04-22 — — CN disclosed
EP-1994145-A2 PRODUCTION OF BIOLOGICALLY ACTIVE PROTEINS ERA Biotech, S.A. (ES) 2008-11-26 — — EP disclosed
US-20070243198-A1 Production of biologically active proteins ERA BIOTECH, S.A. (ES) 2007-10-18 — — US disclosed
WO-2007096192-A2 PRODUCTION OF BIOLOGICALLY ACTIVE PROTEINS ERA BIOTECH, S.A. (ES) 2007-08-30 — — WO disclosed
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