Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | PRNP | P04156 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4143858 | 0.91 | ADORA2A (0.40) | ADORA2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL4125999 | 0.86 | USP2 (0.45) | ADORA2AALDH1A1KDM4EHSD17B10RXFP1 | |
| SCHEMBL13905625 | 0.83 | ADORA2A (0.39) | ADORA2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL13914368 | 0.79 | ALDH1A1 (0.35) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL4053471 | 0.76 | ADORA1 (0.41) | ADORA2AALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL4143728 | 0.76 | ADORA1 (0.41) | ADORA2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL13905624 | 0.73 | ADORA2A (0.40) | ADORA2AALDH1A1LMNANPSR1ADORA1 | |
| SCHEMBL13905626 | 0.73 | ADORA1 (0.38) | ADORA2AALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL4143666 | 0.71 | ADORA2A (0.41) | ADORA2AALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL4129468 | 0.69 | MEN1 (0.39) | ADORA2AALDH1A1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090060867-A1 | PHOSPHADIAZINE HCV POLYMERASE INHIBITORS III AND VI | IDENIX PHARMACEUTICALS, INC. (US) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090060867-A1 | PHOSPHADIAZINE HCV POLYMERASE INHIBITORS III AND VI | POLR2E, POLR2H, POLI | ADORA2A 2513/4885ALDH1A1 1965/4885KDM4E 3262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.