Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13651178 | 1.00 | MAPK1 (0.65) | MAPK1PKMNPSR1ALDH1A1MEN1 | |
| SCHEMBL4132061 | 1.00 | MAPK1 (0.65) | MAPK1PKMNPSR1ALDH1A1MEN1 | |
| SCHEMBL4136593 | 0.91 | MAPK1 (0.61) | MAPK1PKMNPSR1ALDH1A1MEN1 | |
| SCHEMBL4136582 | 0.91 | MAPK1 (0.61) | MAPK1PKMNPSR1ALDH1A1MEN1 | |
| SCHEMBL4136588 | 0.91 | MAPK1 (0.61) | MAPK1PKMNPSR1ALDH1A1MEN1 | |
| SCHEMBL4131316 | 0.84 | PTPN1 (0.65) | MAPK1PKMMEN1KMT2AAKR1B1 | |
| SCHEMBL4131315 | 0.84 | PTPN1 (0.65) | MAPK1PKMMEN1KMT2AAKR1B1 | |
| SCHEMBL5459959 | 0.82 | MAPK1 (0.69) | MAPK1PKMNPSR1ALDH1A1MEN1 | |
| SCHEMBL5459960 | 0.82 | MAPK1 (0.69) | MAPK1PKMNPSR1ALDH1A1MEN1 | |
| SCHEMBL4129765 | 0.82 | ALDH1A1 (0.54) | MAPK1PKMNPSR1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247516-A1 | 3- (BENZO [D] [1,3] DIOXOL-5-YLMETHYL) -4- (THIO) OXO-2- (THIO) OXO-AZOLIDIN-5-YLIDENE DERIVATIVES AS ANTIBACTERIAL AGENTS | KOTNIK MIHA | 2009-10-01 | — | — | US | disclosed |
| EP-1916249-A1 | 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(thio)oxo-2-(thio)oxo-azolidin-5-ylidene derivatives as antibacterial agents | LEK Pharmaceuticals D.D. (SI) | 2008-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247516-A1 | 3- (BENZO [D] [1,3] DIOXOL-5-YLMETHYL) -4- (THIO) OXO-2- (THIO) OXO-AZOLIDIN-5-YLIDENE DERIVATIVES AS ANTIBACTERIAL AGENTS | XDH, TXLNA, Q6ZSR9 | MAPK1 3035/4885PKM 2638/4885NPSR1 751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.