Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.73 |
| ▸ | ICMT | O60725 | 1/20 | 0.67 |
| ▸ | ALB | P02768 | 1/20 | 0.67 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.62 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.62 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.62 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.62 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.62 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.62 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.62 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.62 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.62 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.62 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.62 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.62 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.62 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23271170 | 1.00 | HDAC3 (0.73) | HDAC3HDAC1HDAC2HDAC6ICMT | |
| SCHEMBL12215281 | 1.00 | HDAC3 (0.73) | HDAC3HDAC1HDAC2HDAC6ICMT | |
| Hydrochloric Acid SCHEMBL23271160 | 0.98 | HDAC3 (0.71) | HDAC3HDAC1HDAC2HDAC6ICMT | |
| SCHEMBL27561607 | 0.98 | HDAC3 (0.71) | HDAC3HDAC1HDAC2HDAC6ICMT | |
| SCHEMBL18425276 | 0.93 | HDAC3 (0.68) | HDAC3HDAC1HDAC2HDAC6ICMT | |
| SCHEMBL9510547 | 0.91 | ENPP2 (0.71) | HDAC3HDAC1HDAC2HDAC6PSMB11 | |
| SCHEMBL675018 | 0.91 | ENPP2 (0.71) | HDAC3HDAC1HDAC2HDAC6PSMB11 | |
| SCHEMBL9858666 | 0.91 | ENPP2 (0.71) | HDAC3HDAC1HDAC2HDAC6PSMB11 | |
| SCHEMBL22299223 | 0.89 | HDAC3 (0.59) | HDAC3HDAC1HDAC2HDAC6ICMT | |
| SCHEMBL8075597 | 0.86 | TP53 (0.72) | HDAC3HDAC1HDAC2HDAC6ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | TOUCH BIONICS LIMITED (GB) | 2009-07-30 | — | — | US | disclosed |
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | TOUCH BIONICS LIMITED (GB) | 2009-07-30 | — | — | US | disclosed |
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | TOUCH BIONICS LIMITED (GB) | 2009-07-30 | — | — | US | disclosed |
| WO-2009077844-A2 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | QUONOVA LLC (US) | 2009-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | PGLS, TFPI, Q6ZSR9 | HDAC3 453/4885HDAC1 742/4885HDAC2 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.