⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251442 | 0.85 | ALDH1A1 (0.33) | — | |
| SCHEMBL1154 | 0.85 | — | — | |
| SCHEMBL29284756 | 0.82 | — | — | |
| SCHEMBL6498291 | 0.82 | — | — | |
| Methylene Chloride SCHEMBL1778622 | 0.82 | — | — | |
| SCHEMBL198424 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL7542079 | 0.80 | TSHR (0.32) | — | |
| SCHEMBL15821191 | 0.80 | — | — | |
| SCHEMBL15674477 | 0.80 | — | — | |
| SCHEMBL5140016 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084841-A | Synthesis method of high-purity delta-lactone | 江西香海生物科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-116354995-A | Boron-containing chiral allyl ester compound and high-stereoselectivity synthesis method | 武汉大学 | 2023-06-30 | — | — | CN | claimed |
| CN-111454150-B | Synthesis method of (S) -2-aryl propionate compound | 南京工业大学 | 2023-03-28 | — | — | CN | claimed |
| CN-111423299-B | Photochemical catalytic synthesis method of aryl olefin compound | 北京工商大学 | 2023-03-10 | — | — | CN | claimed |
| CN-115772133-A | Preparation method of bis-ethylhexyloxyphenol methoxyphenyl triazine | 安徽英特美科技有限公司 | 2023-03-10 | — | — | CN | claimed |
| CN-115536572-A | Sulfonyl hydrazide compound and preparation method and application thereof | 中国科学技术大学 | 2022-12-30 | — | — | CN | claimed |
| CN-111039822-B | Photochemical catalytic synthesis method of aromatic azo compound | 北京工商大学 | 2022-11-11 | — | — | CN | claimed |
| CN-111423331-B | Photochemical catalytic synthesis method of aryl alkyl ether | 北京工商大学 | 2022-11-11 | — | — | CN | claimed |
| CN-114805170-A | Preparation method of novel silodosin chiral intermediate | 四川青木制药有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-110256205-B | Method for removing olefin protective group by nickel catalysis | 常熟理工学院 | 2022-02-11 | — | — | CN | claimed |
| CN-113666862-A | Method for preparing chiral 3-nitroindole compound by nickel-catalyzed asymmetric nitration reaction | 山东大学 | 2021-11-19 | — | — | CN | claimed |
| CN-109096149-B | Process for the preparation of beta-arylamines | 富兰克科技（深圳）股份有限公司 | 2021-02-26 | — | — | CN | claimed |
| CN-111454150-A | Synthesis method of (S) -2-aryl propionate compound | 南京工业大学 | 2020-07-28 | — | — | CN | claimed |
| US-12037324-B2 | Biarylmethyl heterocycles | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-07-16 | — | — | US | disclosed |
| CN-118201921-A | Lactams as CBL-B inhibitors selective for C-CBL | 基因泰克公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2024114704-A1 | NOVEL IRAK4 INHIBITOR, AND COMPOUND FOR INHIBITING AND DEGRADING IRAK4 PROTEIN AND PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳众格生物科技有限公司 | 2024-06-06 | — | — | WO | disclosed |
| US-8232274-B2 | Pyridazinone derivatives useful as glucan synthase inhibitors | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-07-31 | — | — | US | disclosed |
| EP-2137179-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2009-12-30 | — | — | EP | disclosed |
| US-20090170861-A1 | Pyridazinone Derivatives Useful as Glucan Synthase Inhibitors | SCHERING CORPORATION AND ALBANY MOLECULAR RESEARCH, INC. | 2009-07-02 | — | — | US | disclosed |
| WO-2008115381-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2008-09-25 | — | — | WO | disclosed |