⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL22664710 | 0.89 | CA2 (0.39) | — | |
| Methylene Chloride SCHEMBL28327323 | 0.89 | CA2 (0.39) | — | |
| Methylene Chloride SCHEMBL28083718 | 0.89 | CA2 (0.39) | — | |
| Methylene Chloride SCHEMBL28142452 | 0.89 | CA2 (0.39) | — | |
| 1,2-Dichloroethane SCHEMBL2366389 | 0.87 | ALDH1A1 (0.42) | — | |
| SCHEMBL251442 | 0.85 | ALDH1A1 (0.33) | — | |
| SCHEMBL1154 | 0.85 | — | — | |
| SCHEMBL4132479 | 0.82 | — | — | |
| SCHEMBL6498291 | 0.82 | — | — | |
| SCHEMBL15821191 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106470974-B | For treating the compound of virus infection | 韩国巴斯德研究所 | 2019-07-16 | — | — | CN | disclosed |
| CN-102134230-B | Dipeptidyl peptidase inhibitors | 武田药品工业株式会社 | 2019-06-28 | — | — | CN | disclosed |
| CN-109071745-A | Cyanate ester compound, method for producing same, resin composition, cured product, prepreg, sealing material, fiber-reinforced composite material, adhesive, metal foil-clad laminate, resin sheet, and printed wiring board | 三菱瓦斯化学株式会社 | 2018-12-21 | — | — | CN | disclosed |
| CN-108779090-A | 2 ring heterocyclic compounds | 大日本住友制药株式会社 | 2018-11-09 | — | — | CN | disclosed |
| CN-104540826-B | Spiro-fused piperidine derivatives useful as inhibitors of extrarenal potassium channels | 默沙东公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-107615536-A | Primary coat paper tinsel for energy storage device electrode | 日产化学工业株式会社 | 2018-01-19 | — | — | CN | disclosed |
| CN-105308024-B | The nitrogenous heteroaromatic amide compound of two ring types | 安斯泰来制药株式会社 | 2017-10-27 | — | — | CN | disclosed |
| CN-107207520-A | Substituted bridged ring urea analogs as sirtuin modulators | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-107207509-A | Substituted bridged ring urea analogs as sirtuin modulators | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-107108627-A | It is used as the substituted bridged ring urea analog of Sirtuin conditioning agent | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2017-08-29 | — | — | CN | disclosed |
| US-4245097-A | 4-[(Monosubstituted-alkyl) amino] benzoic acids and analogs as hypolipidemic and antiatherosclerotic agents | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | disclosed |
| US-4243609-A | ANTILIPEMIC AGENTS, ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4242273-A | ANTILIPEMIC AND ANTICHOLESTEROL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| US-4230878-A | AND 4-(UNSATURATED ALKYL)AMINOBENZOIC ACIDS AND DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1980-10-28 | — | — | US | disclosed |
| US-4230628-A | HYPOLIPIDEMIC AGENTS, ANTIATHEROSCLEROSIS | AMERICAN CYANAMID COMPANY (US) | 1980-10-28 | — | — | US | disclosed |
| US-4227014-A | ANTILIPEMIC AGENTS, ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| US-4205085-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino)phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1980-05-27 | — | — | US | disclosed |
| US-4196208-A | ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | disclosed |
| US-4136256-A | HYPOLIPIDEMIC, ANTIATHEROSCLEROTIC | AMERICAN CYANAMID COMPANY (US) | 1979-01-23 | — | — | US | disclosed |