Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 11/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126185 | 1.00 | BDKRB1 (0.57) | BDKRB1THRBOPRD1TSHR | |
| SCHEMBL4125392 | 0.83 | BDKRB1 (0.61) | BDKRB1THRB | |
| SCHEMBL3404279 | 0.82 | BDKRB1 (0.62) | BDKRB1THRB | |
| SCHEMBL3413328 | 0.79 | BDKRB1 (0.58) | BDKRB1THRB | |
| SCHEMBL642922 | 0.77 | BDKRB1 (0.62) | BDKRB1THRBOPRD1 | |
| SCHEMBL2487757 | 0.76 | BDKRB1 (0.59) | BDKRB1THRBOPRD1TSHR | |
| SCHEMBL643279 | 0.73 | BDKRB1 (0.58) | BDKRB1THRBTSHR | |
| SCHEMBL644218 | 0.73 | BDKRB1 (0.60) | BDKRB1THRBOPRD1 | |
| SCHEMBL645088 | 0.72 | BDKRB1 (0.58) | BDKRB1THRBTSHR | |
| SCHEMBL4119477 | 0.70 | BDKRB1 (0.47) | BDKRB1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | claimed |
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | BDKRB1 3589/4885THRB 4066/4885OPRD1 2056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.