Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29454770 | 1.00 | ALDH1A1 (0.54) | ALDH1A1ALOX15KAT6ATSHRCES2 | |
| SCHEMBL19185970 | 0.86 | ALDH1A1 (0.62) | ALDH1A1ALOX15KAT6ATSHRCES2 | |
| SCHEMBL9693738 | 0.83 | KAT6A (0.47) | ALDH1A1ALOX15KAT6ATSHRCES2 | |
| SCHEMBL401838 | 0.83 | TSHR (0.63) | ALDH1A1ALOX15KAT6ATSHRCES2 | |
| SCHEMBL30462062 | 0.83 | TSHR (0.63) | ALDH1A1ALOX15KAT6ATSHRCES2 | |
| SCHEMBL3612002 | 0.81 | KAT6A (0.46) | ALDH1A1KAT6ATSHRCES2CES1 | |
| Hydrochloric Acid SCHEMBL10557491 | 0.81 | TSHR (0.61) | ALDH1A1ALOX15KAT6ATSHRCES2 | |
| SCHEMBL29975438 | 0.81 | PBRM1 (0.49) | ALDH1A1KAT6ATSHRCES2CES1 | |
| SCHEMBL2175638 | 0.81 | PBRM1 (0.49) | ALDH1A1KAT6ATSHRCES2CES1 | |
| SCHEMBL17738209 | 0.80 | KAT6A (0.54) | ALDH1A1KAT6APOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503562-A | Bis[5-fluro-2-(4'-methoxybenzoyl)]biphenyl and synthetic method thereof | UNIV NANJING SCIENCE & TECH | 2016-04-20 | — | — | CN | claimed |
| CN-103524487-B | A kind of preparation method of Sitafloxacin | NANJING YOKO BIO-MEDICAL RESEARCH CO., LTD. (CN) | 2015-12-02 | — | — | CN | claimed |
| CN-104529735-A | 1-(5-bromo-4-chloro-2-fluorophenyl)-ethanone synthesis method | SUZHOU SHIYA BIOPHARMACEUTICALS INC | 2015-04-22 | — | — | CN | claimed |
| CN-103524487-A | Sitafloxacin preparation method | NANJING YOKO BIO MEDICAL RES CO LTD | 2014-01-22 | — | — | CN | claimed |
| CN-114213310-B | Indoline compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2024-02-23 | — | — | CN | disclosed |
| WO-2023125473-A1 | INDOLINE COMPOUNDS AND DERIVATIVES THEREOF, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国药科大学 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023125473-A1 | INDOLINE COMPOUNDS AND DERIVATIVES THEREOF, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国药科大学 | 2023-07-06 | — | — | WO | disclosed |
| US-11464783-B2 | Heterocyclic compounds | ALIGOS THERAPEUTICS, INC. (US) | 2022-10-11 | — | — | US | disclosed |
| CN-113061098-B | Amide compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-114213310-A | Indoline compound and derivative, preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-108698982-B | Fluorine atom-containing compound and use thereof | 日产化学工业株式会社 | 2021-07-16 | — | — | CN | disclosed |
| CN-113061098-A | Amide compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2021-07-02 | — | — | CN | disclosed |
| WO-2001047859-A1 | COMPOUNDS ACTIVE AT THE GLUCOCORTICOID RECEPTOR | KARO BIO AB (SE) | 2001-07-05 | — | — | WO | disclosed |
| CN-1031378-C | Combating insect infestation in rice | ROHM & HAAS (US) | 1996-03-27 | — | — | CN | disclosed |
| CN-1030911-C | Dibenzoylalkylcyanohydrazines | ROHM & HAAS (US) | 1996-02-07 | — | — | CN | disclosed |
| EP-0461809-B1 | Dibenzoylalkylcyanohydrazines | ROHM & HAAS (US) | 1994-12-07 | — | — | EP | disclosed |
| CN-1057452-A | Dibenzoyl alkyl-alkyl cyanides | ROHM & HAAS (US) | 1992-01-01 | — | — | CN | disclosed |
| EP-0461809-A1 | Dibenzoylalkylcyanohydrazines | ROHM AND HAAS COMPANY (US) | 1991-12-18 | — | — | EP | disclosed |
| CN-1046835-A | Go out and remove the method for rice insect pest | ROHM & HAAS (US) | 1990-11-14 | — | — | CN | disclosed |
| US-4876382-A | Process for making fluorobenzoic acid fluorophenylesters | CENTRAL GLASS COMPANY, LIMITED (JP) | 1989-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11464783-B2 | Heterocyclic compounds | SLC10A1, CFTR, PKD1 | ALDH1A1 296/4885ALOX15 2109/4885KAT6A 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.