Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23502399 | 0.81 | KDM4C (0.44) | KDM4CCA1CA2CTSSCTSK | |
| SCHEMBL13821724 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10CA1CA2 | |
| SCHEMBL10031576 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10CA1CA2 | |
| SCHEMBL4141413 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10CA1CA2 | |
| SCHEMBL24882649 | 0.78 | PIK3CD (0.36) | ALDH1A1KDM4EHSD17B10RAB9ACA1 | |
| SCHEMBL9911469 | 0.78 | KDM4C (0.42) | KDM4CALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL29757439 | 0.78 | KDM4C (0.44) | KDM4CALDH1A1CA1CA2CTSS | |
| SCHEMBL29858297 | 0.77 | KDM4C (0.41) | KDM4CMMEACECPA1ACE2 | |
| SCHEMBL19392024 | 0.77 | EPHX1 (0.39) | ALDH1A1KDM4EHSD17B10CA1CA2 | |
| SCHEMBL9966002 | 0.77 | EPHX1 (0.39) | ALDH1A1KDM4EHSD17B10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716422-B2 | Anionic charge-dynamic polymers for release of cationic agents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-05-06 | — | — | US | disclosed |
| US-8574420-B2 | Ultrathin multilayered films for controlled release of anionic reagents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-11-05 | — | — | US | disclosed |
| US-20130122055-A1 | Anionic Charge-Dynamic Polymers for Release of Cationic Agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-05-16 | — | — | US | disclosed |
| US-8324333-B2 | Anionic charge-dynamic polymers for release of cationic agents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-12-04 | — | — | US | disclosed |
| US-20120065616-A1 | Ultrathin Multilayered Films for Controlled Release of Anionic Reagents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-03-15 | — | — | US | disclosed |
| US-20100048736-A1 | ANIONIC CHARGE-DYNAMIC POLYMERS FOR RELEASE OF CATIONIC AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-02-25 | — | — | US | disclosed |
| US-20090105375-A1 | Ultrathin Multilayered Films for Controlled Release of Anionic Reagents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130122055-A1 | Anionic Charge-Dynamic Polymers for Release of Cationic Agents | PARG, PARN, CHMP4B | KDM4C 1269/4885ALDH1A1 4817/4885KDM4E 955/4885 |
| US-20100048736-A1 | ANIONIC CHARGE-DYNAMIC POLYMERS FOR RELEASE OF CATIONIC AGENTS | PARG, PARN, CHMP4B | KDM4C 1269/4885ALDH1A1 4817/4885KDM4E 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.