Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 15/20 | 1.00 |
| ▸ | FYN | P06241 | 1/20 | 0.61 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.56 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133334 | 1.00 | SRC (1.00) | SRCFYNMAP2K1MAP3K8 | |
| SCHEMBL3221419 | 0.95 | SRC (0.91) | SRCFYNMAP2K1MAP3K8 | |
| SCHEMBL3221409 | 0.95 | SRC (0.91) | SRCFYNMAP2K1MAP3K8 | |
| SCHEMBL3228318 | 0.94 | SRC (0.90) | SRCFYNMAP2K1 | |
| SCHEMBL3228309 | 0.94 | SRC (0.90) | SRCFYNMAP2K1 | |
| SCHEMBL4117621 | 0.94 | SRC (0.88) | SRCFYNMAP2K1 | |
| SCHEMBL4117615 | 0.94 | SRC (0.88) | SRCFYNMAP2K1 | |
| SCHEMBL4127676 | 0.94 | SRC (1.00) | SRCFYNMAP3K8 | |
| SCHEMBL4127682 | 0.94 | SRC (1.00) | SRCFYNMAP3K8 | |
| SCHEMBL4129547 | 0.92 | SRC (0.85) | SRCFYNMAP2K1MAP3K8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099356-A1 | PREPARATION OF 7-ALKENYL-3 QUINOLINECARBONITRILES VIA A PALLADIUM MEDIATED COUPLING REACTION | WYETH (US) | 2009-04-16 | — | — | US | claimed |
| US-20090099356-A1 | PREPARATION OF 7-ALKENYL-3 QUINOLINECARBONITRILES VIA A PALLADIUM MEDIATED COUPLING REACTION | WYETH (US) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099356-A1 | PREPARATION OF 7-ALKENYL-3 QUINOLINECARBONITRILES VIA A PALLADIUM MEDIATED COUPLING REACTION | PARK7, UQCRB, PRMT7 | SRC 3605/4885FYN 1861/4885MAP2K1 2266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.