Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.36 |
| ▸ | HTR2B | P41595 | 9/20 | 0.36 |
| ▸ | HTR2A | P28223 | 7/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992310 | 0.88 | HTR2C (0.39) | HTR2CHTR2BHTR2AMAPK1KDM1A | |
| SCHEMBL3769425 | 0.84 | HTR2A (0.46) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL828122 | 0.83 | HTR2C (0.42) | HTR2CHTR2BHTR2A | |
| SCHEMBL27561229 | 0.83 | SLC6A2 (0.44) | HTR2CHTR2BHTR2AMAPK1 | |
| SCHEMBL28738216 | 0.79 | ALDH1A1 (0.34) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL2649062 | 0.78 | GPR119 (0.36) | HTR2CHTR2BHTR2AMAPK1 | |
| SCHEMBL30175676 | 0.77 | ACACB (0.31) | HTR2CHTR2BHTR2A | |
| SCHEMBL3764752 | 0.77 | HTR2C (0.37) | HTR2CHTR2BHTR2AMAPK1 | |
| SCHEMBL28738154 | 0.76 | HTR2C (0.34) | HTR2CHTR2BHTR2A | |
| SCHEMBL31026017 | 0.76 | ALDH1A1 (0.33) | HTR2CHTR2BHTR2AHTR6BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163715-A1 | Intermediate in Production of [2-(3,3,5,5-Tetramethylcyclohexyl)phenyl]Piperazine Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-25 | — | — | US | disclosed |
| EP-1889827-A1 | INTERMEDIATE IN PRODUCTION OF [2-(3,3,5,5-TETRAMETHYLCYCLOHEXYL)PHENYL]PIPERAZINE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2008-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163715-A1 | Intermediate in Production of [2-(3,3,5,5-Tetramethylcyclohexyl)phenyl]Piperazine Compound | ICAM1, HRH1, HRH2 | HTR2C 1381/4885HTR2B 1681/4885HTR2A 1798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.