Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10758020 | 1.00 | ALDH1A1 (0.44) | ALDH1A1PKMHPGDKCNH2GPR84 | |
| SCHEMBL27983100 | 1.00 | ALDH1A1 (0.44) | ALDH1A1PKMHPGDKCNH2GPR84 | |
| SCHEMBL3846855 | 0.92 | HRH3 (0.41) | ALDH1A1PKMHPGDKCNH2GPR84 | |
| SCHEMBL10697416 | 0.91 | KCNH2 (0.50) | ALDH1A1PKMHPGDKCNH2GPR84 | |
| SCHEMBL9817100 | 0.91 | KCNH2 (0.50) | ALDH1A1PKMHPGDKCNH2GPR84 | |
| SCHEMBL730079 | 0.91 | KCNH2 (0.50) | ALDH1A1PKMHPGDKCNH2GPR84 | |
| SCHEMBL4445935 | 0.91 | KCNH2 (0.50) | ALDH1A1PKMHPGDKCNH2GPR84 | |
| SCHEMBL9133514 | 0.91 | KCNH2 (0.50) | ALDH1A1PKMHPGDKCNH2GPR84 | |
| SCHEMBL28413083 | 0.91 | KCNH2 (0.50) | ALDH1A1PKMHPGDKCNH2GPR84 | |
| SCHEMBL27668867 | 0.91 | KCNH2 (0.50) | ALDH1A1PKMHPGDKCNH2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420764-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20120178894-A1 | COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER | INAGAKI JYUN-ICHI (JP) | 2012-07-12 | — | — | US | disclosed |
| US-7507782-B2 | Transition-metal complexes with tridentate, nitrogen-containing ligands | BASELL POLYOLEFINE GMBH (DE) | 2009-03-24 | — | — | US | disclosed |
| US-20070185328-A1 | Transition-metal complexes with tridentate, nitrogen-containing ligands | MIHAN SHAHRAM | 2007-08-09 | — | — | US | disclosed |
| EP-1625168-A1 | TRANSITION-METAL COMPLEXES WITH TRIDENTATE, NITROGEN-CONTAINING LIGANDS | Basell Polyolefine GmbH (DE) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004104052-A1 | TRANSITION-METAL COMPLEXES WITH TRIDENTATE, NITROGEN-CONTAINING LIGANDS | BASELL POLYOLEFINE GMBH (DE) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185328-A1 | Transition-metal complexes with tridentate, nitrogen-containing ligands | NMT1, TNS4, PUF60 | ALDH1A1 4614/4885PKM 2851/4885HPGD 1635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.