⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2524574 | 0.82 | — | — | |
| SCHEMBL30709586 | 0.80 | ACHE (0.32) | — | |
| Ethylene Glycol SCHEMBL10584826 | 0.78 | ALDH1A1 (0.31) | — | |
| Ethylene Glycol SCHEMBL413417 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL3497998 | 0.78 | — | — | |
| SCHEMBL2335942 | 0.76 | — | — | |
| SCHEMBL3748421 | 0.76 | — | — | |
| Ethylene SCHEMBL4367126 | 0.76 | — | — | |
| SCHEMBL3719747 | 0.76 | ALDH1A1 (0.34) | — | |
| SCHEMBL5613498 | 0.76 | POLB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2138575-B1 | Conjugates comprising a biodegradable polymer and uses therefor | MERSANA THERAPEUTICS INC (US) | 2013-06-19 | — | — | EP | claimed |
| US-20110044967-A1 | Conjugates Comprising a Biodegradable Polymer and Uses Therefor | THE GENERAL HOSPITAL CORPORATION | 2011-02-24 | — | — | US | claimed |
| EP-2138575-A1 | Conjugates comprising a biodegradable polymer and uses therefor | The General Hospital Corporation (US) | 2009-12-30 | — | — | EP | claimed |
| EP-1585817-B1 | CONJUGATES COMPRISING A BIODEGRADABLE POLYMER AND USES THEREFOR | GEN HOSPITAL CORP (US) | 2009-09-02 | — | — | EP | claimed |
| US-20050169968-A1 | Conjugates comprising a biodegradable polymer and uses therefor | THE GENERAL HOSPITAL CORPORATION | 2005-08-04 | — | — | US | claimed |
| US-20050059068-A1 | Compositions and methods using dendrimer-treated microassays | STRATAGENE CALIFORNIA | 2005-03-17 | — | — | US | claimed |
| WO-1995021380-A1 | ASSAY FOR SCREENING OF RECEPTOR ANTAGONISTS | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 1995-08-10 | — | — | WO | claimed |
| US-20160334404-A1 | VALUE-ASSIGNED SOLUTIONS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 HAVING A LONG SHELF-LIFE | DIAZYME LABORATORIES, INC. | 2016-11-17 | — | — | US | disclosed |
| EP-3049813-A2 | LONG SHELF-LIFE KITS AND METHODS FOR STANDARDIZING, VERIFYING, CALIBRATING OR RECALIBRATING DETECTION OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | Diadexus, Inc. (US) | 2016-08-03 | — | — | EP | disclosed |
| US-9297800-B2 | Biomaterial construct, its producing method, biomaterial support, target material purifying method, affinity chromatography container, separation chip, analyzing method and analyzing separator for target material, biomaterial complex, and its support, sensor chip, solid support with biomaterial fixed thereon | MITSUBISHI CHEMICAL CORPORATION (JP) | 2016-03-29 | — | — | US | disclosed |
| WO-2015048177-A2 | LONG SHELF-LIFE KITS AND METHODS FOR STANDARDIZING, VERIFYING, CALIBRATING OR RECALIBRATING DETECTION OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | DIADEXUS, INC. (US) | 2015-04-02 | — | — | WO | disclosed |
| US-20150086998-A1 | VALUE-ASSIGNED SOLUTIONS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 HAVING A LONG SHELF-LIFE | DIAZYME LABORATORIES, INC. | 2015-03-26 | — | — | US | disclosed |
| US-20150086999-A1 | LONG SHELF-LIFE KITS AND METHODS FOR STANDARDIZING, VERIFYING, CALIBRATING OR RECALIBRATING DETECTION OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | DIAZYME LABORATORIES, INC. | 2015-03-26 | — | — | US | disclosed |
| WO-2001049720-A2 | CHEMICALLY MODIFIED HIV ENVELOPE GLYCOPROTEIN | AVENTIS PASTEUR (FR) | 2001-07-12 | — | — | WO | disclosed |
| EP-1100926-A1 | TRIMER OF HIV $i(ENV) GENE EXPRESSION PRODUCT | Aventis Pasteur (FR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000008167-A1 | TRIMER OF HIV ENV GENE EXPRESSION PRODUCT | AVENTIS PASTEUR (FR) | 2000-02-17 | — | — | WO | disclosed |
| US-5935932-A | Bradykinin antagonists containing pentafluorophenylalanine | UNIVERSITY TECHNOLOGY CORPORATION (US) | 1999-08-10 | — | — | US | disclosed |
| US-5916585-A | POLYMERIC SURFACTANTS ATTACHED ONTO THE SURFACES OF A SUPPORT MEMBER AND COVALENTLY CROSS-LINKED THEREON TO FORM A FIRST LAYER. HYDROPHILIC POLYMERS ARE THEN ATTACHED TO THE FIRST LAYER ON THE SUPPORT MEMBER TO FORM A SECOND LAYER THEREON. | GORE ENTERPRISE HOLDINGS, INC. (US) | 1999-06-29 | — | — | US | disclosed |
| US-5876976-A | Method for reducing carryover contamination in an amplification procedure | AMGEN INC. (US) | 1999-03-02 | — | — | US | disclosed |
| WO-1995021380-A1 | ASSAY FOR SCREENING OF RECEPTOR ANTAGONISTS | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 1995-08-10 | — | — | WO | disclosed |