Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701801 | 0.77 | MEN1 (0.30) | MEN1GLACYP2C19KMT2A | |
| SCHEMBL11775833 | 0.73 | CYP2C19 (0.36) | MEN1GLACYP2C19KMT2A | |
| SCHEMBL28219537 | 0.70 | CYP2C19 (0.38) | MEN1GLACYP2C19KMT2A | |
| SCHEMBL8661679 | 0.68 | GNAI3 (0.38) | MEN1KMT2A | |
| SCHEMBL11742072 | 0.67 | CYP2C19 (0.35) | MEN1GLACYP2C19KMT2A | |
| SCHEMBL11123620 | 0.67 | CYP2C19 (0.43) | MEN1GLACYP2C19KMT2A | |
| SCHEMBL2162868 | 0.67 | — | — | |
| SCHEMBL4290333 | 0.67 | — | — | |
| SCHEMBL12501989 | 0.65 | — | — | |
| SCHEMBL4455326 | 0.65 | CYP2C19 (0.39) | MEN1GLACYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110942-A2 | GENERATION OF COMBINATORIAL SYNTHETIC LIBRARIES AND SCREENING FOR NOVEL PROADHESINS AND NONADHESINS | CERNOFINA, LLC (US) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009076618-A2 | GENERATION OF COMBINATORIAL SYNTHETIC LIBRARIES AND SCREENING FOR NOVEL PROADHESINS AND NONADHESINS | CERNOFINA, LLC (US) | 2009-06-18 | — | — | WO | disclosed |