Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8643825 | 0.76 | DNM1 (0.35) | GNAI3GNAO1GNAI1DNM1MEN1 | |
| SCHEMBL11511106 | 0.76 | CYP2D6 (0.40) | GNAI3GNAO1GNAI1ALDH1A1EPHX1 | |
| SCHEMBL22188164 | 0.75 | DNM1 (0.46) | GNAI3GNAO1GNAI1DNM1MEN1 | |
| SCHEMBL350373 | 0.73 | DNM1 (0.65) | GNAI3GNAO1GNAI1DNM1MEN1 | |
| SCHEMBL29230040 | 0.72 | DNM1 (0.44) | GNAI3GNAO1GNAI1DNM1MEN1 | |
| SCHEMBL22788210 | 0.72 | ALDH1A1 (0.37) | DNM1ALDH1A1TSHRSPHK1DPP8 | |
| SCHEMBL27753480 | 0.71 | DNM1 (0.42) | GNAI3GNAO1GNAI1DNM1MEN1 | |
| SCHEMBL23034836 | 0.70 | DNM1 (0.53) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11207922 | 0.70 | DNM1 (0.53) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11212697 | 0.70 | DNM1 (0.53) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719193-A | Method of potentiating cell-mediated immunity utilizing polyamine derivatives | MERRELL PHARMACEUTICALS, INC. (US) | 1998-02-17 | — | — | US | claimed |