SCHEMBL4134334

SCHEMBL4134334

CN(C)c1cccc2c(S(=O)(=O)NC(Cc3ccccc3)C(=O)O)cccc12

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TYMS P04818 5/20 0.65
F2 P00734 2/20 0.63
F10 P00742 1/20 0.53
ALDH1A1 P00352 1/20 0.53
MAPT P10636 1/20 0.53
MMP2 P08253 4/20 0.52
MMP9 P14780 3/20 0.52
ADAMTS4 O75173 1/20 0.52
USP30 Q70CQ3 1/20 0.52
EDNRA P25101 1/20 0.50
PTGS2 P35354 1/20 0.50
POLB P06746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4134328 1.00 TYMS (0.65) TYMSF2F10ALDH1A1MAPT
SCHEMBL9052993 1.00 TYMS (0.65) TYMSF2F10ALDH1A1MAPT
SCHEMBL29829755 1.00 TYMS (0.65) TYMSF2F10ALDH1A1MAPT
SCHEMBL29597077 0.92 F2 (0.63) TYMSF2F10EDNRAPTGS2
SCHEMBL27578159 0.92 F2 (0.63) TYMSF2F10EDNRAPTGS2
SCHEMBL29941510 0.88 TYMS (0.81) TYMSF2F10PTGS2
SCHEMBL4325460 0.88 TYMS (0.81) TYMSF2F10PTGS2
SCHEMBL5706271 0.87 TYMS (0.54) TYMSF2EDNRA
SCHEMBL6266410 0.87 TYMS (0.54) TYMSF2EDNRA
SCHEMBL17351925 0.86 TYMS (0.57) TYMSF2F10EDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240189317-A1 ANTIVIRAL COMPOSITIONS AND METHODS ACADIA WOODS PARTNERS, LLC 2024-06-13 US claimed
EP-2934555-B1 METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS ASTELLAS INST FOR REGENERATIVE MEDICINE (US) 2021-09-22 EP claimed
CN-105749890-A Chiral stationary phase prepared by taking cinchonidine-boc-amide as chiral selector as well as preparation method and application thereof 河南科技学院 2016-07-13 CN claimed
CN-105642261-A Chiral stationary phase prepared with cinchonine-Boc-amide as chiral selector and preparation method and application thereof 河南科技学院 2016-06-08 CN claimed
CN-105561959-A Chiral stationary phase prepared by taking quinine-tertiary butyl carbamate as a chiral selector and preparation method and application of chiral stationary phase HENAN INST OF SCIENCE & TECH 2016-05-11 CN claimed
CN-105498736-A Chiral stationary phase prepared by taking quinindium-t-butyl carbamate as chirality selector as well as preparation method and application of chiral stationary phase HENAN INST OF SCIENCE & TECH 2016-04-20 CN claimed
US-5541633-A Ink jet printing of concealed images on carbonless paper XEROX CORPORATION (US) 1996-07-30 US claimed
US-5286286-A Containing diethylene glycol monobutyl ether, glycerol, and a dansyl or porphyrin chromophores XEROX CORPORATION (US) 1994-02-15 US claimed
JP-7146282-A None JP disclosed
CN-119174932-A Preparation method of capillary chromatographic column based on metal organic framework material and used for chiral separation 上海大学 2024-12-24 CN disclosed
CN-114504843-B Preparation method of capillary open-tube chromatographic column based on metal organic framework material 上海大学 2023-05-02 CN disclosed
CN-114504843-A Preparation method of capillary open-tube chromatographic column based on metal organic framework material 上海大学 2022-05-17 CN disclosed
EP-3313566-B1 PREPARATION OF MOLECULARLY IMPRINTED POLYMERS BY TWO-PHOTON STEREOLITHOGRAPHY CENTRE NAT RECH SCIENT (FR) 2019-06-05 EP disclosed
EP-3313566-A1 PREPARATION OF MOLECULARLY IMPRINTED POLYMERS BY TWO-PHOTON STEREOLITHOGRAPHY Centre National De La Recherche Scientifique (FR) 2018-05-02 EP disclosed
EP-1200932-A1 PORTABLE AUTHENTICATION DEVICE AND METHOD OF AUTHENTICATING PRODUCTS OR PRODUCT PACKAGING Verification Technologies, Inc. d/b/a Veritec (US) 2002-05-02 EP disclosed
WO-2001006453-A1 PORTABLE AUTHENTICATION DEVICE AND METHOD OF AUTHENTICATING PRODUCTS OR PRODUCT PACKAGING VERIFICATION TECHNOLOGIES, INC. D/B/A VERITEC (US) 2001-01-25 WO disclosed
US-5629424-A Stereoselective adsorptive bubble process THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 1997-05-13 US disclosed
US-5541633-A Ink jet printing of concealed images on carbonless paper XEROX CORPORATION (US) 1996-07-30 US disclosed
JP-H07146282-A SEPARATION AGENT FOR CHROMATOGRAPHY Y M SHII:KK 1995-06-06 JP disclosed
US-5286286-A Containing diethylene glycol monobutyl ether, glycerol, and a dansyl or porphyrin chromophores XEROX CORPORATION (US) 1994-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240189317-A1 ANTIVIRAL COMPOSITIONS AND METHODS PIKFYVE, APAF1, API5 TYMS 690/4885F2 600/4885F10 1288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.