SCHEMBL9052993

SCHEMBL9052993

CN(C)c1cccc2c(S(=O)(=O)N[C@H](Cc3ccccc3)C(=O)O)cccc12

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TYMS P04818 5/20 0.65
F2 P00734 2/20 0.63
F10 P00742 1/20 0.53
ALDH1A1 P00352 1/20 0.53
MAPT P10636 1/20 0.53
MMP2 P08253 4/20 0.52
MMP9 P14780 3/20 0.52
ADAMTS4 O75173 1/20 0.52
USP30 Q70CQ3 1/20 0.52
EDNRA P25101 1/20 0.50
PTGS2 P35354 1/20 0.50
POLB P06746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4134328 1.00 TYMS (0.65) TYMSF2F10ALDH1A1MAPT
SCHEMBL4134334 1.00 TYMS (0.65) TYMSF2F10ALDH1A1MAPT
SCHEMBL29829755 1.00 TYMS (0.65) TYMSF2F10ALDH1A1MAPT
SCHEMBL29597077 0.92 F2 (0.63) TYMSF2F10EDNRAPTGS2
SCHEMBL27578159 0.92 F2 (0.63) TYMSF2F10EDNRAPTGS2
SCHEMBL29941510 0.88 TYMS (0.81) TYMSF2F10PTGS2
SCHEMBL4325460 0.88 TYMS (0.81) TYMSF2F10PTGS2
SCHEMBL5706271 0.87 TYMS (0.54) TYMSF2EDNRA
SCHEMBL6266410 0.87 TYMS (0.54) TYMSF2EDNRA
SCHEMBL17351925 0.86 TYMS (0.57) TYMSF2F10EDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240189317-A1 ANTIVIRAL COMPOSITIONS AND METHODS ACADIA WOODS PARTNERS, LLC 2024-06-13 US claimed
EP-2934555-B1 METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS ASTELLAS INST FOR REGENERATIVE MEDICINE (US) 2021-09-22 EP claimed
CN-107249578-B Method for treating envenomation and related pharmaceutical composition, system and kit 奥菲瑞克斯股份有限公司 2021-01-26 CN claimed
US-20170354642-A1 ENVENOMATION THERAPIES AND RELATED PHARMACEUTICAL COMPOSITIONS, SYSTEMS AND KITS OPHIREX INC (US) 2017-12-14 US claimed
EP-3220902-A2 ENVENOMATION THERAPIES AND RELATED PHARMACEUTICAL COMPOSITIONS, SYSTEMS AND KITS Ophirex, Inc. (US) 2017-09-27 EP claimed
US-20250090586-A1 METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) 2025-03-20 US disclosed
US-12076347-B2 Methods for production of platelets from pluripotent stem cells and compositions thereof ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) 2024-09-03 US disclosed
WO-2023086343-A1 COMPOSITIONS AND DOSAGE FORMS FOR TOPICAL AND TRANSDERMAL DELIVERY OF ACTIVES AND METHODS OF USE OPHIREX, INC. (US) 2023-05-19 WO disclosed
CN-114504843-B Preparation method of capillary open-tube chromatographic column based on metal organic framework material 上海大学 2023-05-02 CN disclosed
US-20230028239-A1 METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) 2023-01-26 US disclosed
CN-115379836-A Early management and prevention of sepsis and sepsis-like syndrome 奥菲瑞克斯公司 2022-11-22 CN disclosed
US-11400118-B2 Methods for production of platelets from pluripotent stem cells and compositions thereof ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) 2022-08-02 US disclosed
US-9993503-B2 Methods for production of platelets from pluripotent stem cells and compositions thereof ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) 2018-06-12 US disclosed
US-20170354642-A1 ENVENOMATION THERAPIES AND RELATED PHARMACEUTICAL COMPOSITIONS, SYSTEMS AND KITS OPHIREX INC (US) 2017-12-14 US disclosed
EP-3220902-A2 ENVENOMATION THERAPIES AND RELATED PHARMACEUTICAL COMPOSITIONS, SYSTEMS AND KITS Ophirex, Inc. (US) 2017-09-27 EP disclosed
US-20160022736-A1 METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF ADVANCED CELL TECHNOLOGY, INC. (US) 2016-01-28 US disclosed
US-20150313944-A1 METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF OCATA THERAPEUTICS, INC. (US) 2015-11-05 US disclosed
EP-2934555-A1 METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF Ocata Therapeutics, Inc. (US) 2015-10-28 EP disclosed
WO-2014100779-A1 METHODS OFR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF ADVANCED CELL TECHNOLOGY, INC. (US) 2014-06-26 WO disclosed
WO-1996041173-A1 NANOPARTICLES IMPRINTED WITH RECOGNITION SITES FOR TARGET MOLECULES MARTINEX R & D INC. (CA) 1996-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240189317-A1 ANTIVIRAL COMPOSITIONS AND METHODS PIKFYVE, APAF1, API5 TYMS 690/4885F2 600/4885F10 1288/4885
US-20150313944-A1 METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF THPO, PDGFRA, PDGFRB TYMS 1618/4885F2 479/4885F10 299/4885
US-20230028239-A1 METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF THPO, PDGFRA, PDGFRB TYMS 1618/4885F2 479/4885F10 299/4885
US-11400118-B2 Methods for production of platelets from pluripotent stem cells and compositions thereof THPO, PDGFRA, PDGFRB TYMS 1618/4885F2 479/4885F10 299/4885
US-20250090586-A1 METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF THPO, PDGFRA, PDGFRB TYMS 1618/4885F2 479/4885F10 299/4885
US-20170354642-A1 ENVENOMATION THERAPIES AND RELATED PHARMACEUTICAL COMPOSITIONS, SYSTEMS AND KITS PLA2R1, PLA2G12A, ACHE TYMS 1475/4885F2 181/4885F10 246/4885
US-20160022736-A1 METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF THPO, PDGFRA, PDGFRB TYMS 1618/4885F2 479/4885F10 299/4885
US-12076347-B2 Methods for production of platelets from pluripotent stem cells and compositions thereof THPO, PDGFRA, PDGFRB TYMS 1618/4885F2 479/4885F10 299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.