SCHEMBL4134778

SCHEMBL4134778

CSCCC(NS(=O)(=O)c1cccc2c(N(C)C)cccc12)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
PKM P14618 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.52
PKLR P30613 1/20 0.51
TYMS P04818 1/20 0.50
F2 P00734 1/20 0.49
RAB9A P51151 1/20 0.49
RECQL P46063 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4134777 1.00 LMNA (0.57) LMNAPKMSMN1; SMN2PKLRTYMS
Cyclohexylamine SCHEMBL25313860 0.90 F2 (0.54) LMNAPKMTYMSF2
Cyclohexylamine SCHEMBL29475884 0.90 F2 (0.54) LMNAPKMTYMSF2
SCHEMBL179968 0.87 TYMS (0.52) TYMSF2
SCHEMBL179967 0.87 TYMS (0.52) TYMSF2
SCHEMBL13897354 0.87 TYMS (0.52) TYMSF2
SCHEMBL9751607 0.87 TYMS (0.52) TYMSF2
SCHEMBL5149283 0.87 TYMS (0.52) TYMSF2
SCHEMBL3863361 0.86 HDAC4 (0.53) TYMSF2
SCHEMBL3863358 0.86 HDAC4 (0.53) TYMSF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5541633-A Ink jet printing of concealed images on carbonless paper XEROX CORPORATION (US) 1996-07-30 US claimed
US-5286286-A Containing diethylene glycol monobutyl ether, glycerol, and a dansyl or porphyrin chromophores XEROX CORPORATION (US) 1994-02-15 US claimed
US-20240050572-A1 Polysorbate Mixtures Having Modified Fatty Acid Ester Distribution GENENTECH, INC. (US) 2024-02-15 US disclosed
US-11833206-B2 Polysorbate mixtures having modified fatty acid ester distribution GENENTECH, INC. (US) 2023-12-05 US disclosed
EP-4217003-A1 POLYSORBATE MIXTURES HAVING MODIFIED FATTY ACID ESTER DISTRIBUTION Genentech, Inc. (US) 2023-08-02 EP disclosed
CN-116528906-A Polysorbate blends with modified fatty acid ester distribution 基因泰克公司 2023-08-01 CN disclosed
US-20220111054-A1 POLYSORBATE MIXTURES HAVING MODIFIED FATTY ACID ESTER DISTRIBUTION GENENTECH, INC. (US) 2022-04-14 US disclosed
WO-2022066858-A1 POLYSORBATE MIXTURES HAVING MODIFIED FATTY ACID ESTER DISTRIBUTION GENENTECH, INC. (US) 2022-03-31 WO disclosed
EP-0748247-B1 Macrocyclic antibiotics as separation agents UNIV MISSOURI (US) 2012-06-20 EP disclosed
US-20090008452-A1 PRODUCT PACKAGING INCLUDING DIGITAL DATA VERIFICATION TECHNOLOGIES, INC. (US) 2009-01-08 US disclosed
US-20080011853-A1 Product Packaging Including Digital Data VERIFICATION TECHNOLOGIES, INC. (US) 2008-01-17 US disclosed
US-5874005-A SEPARATION OF ENANTIOMORPHS IN SOLUTION; CHROMATOGRAPHY, ELECTROPHORESIS THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 1999-02-23 US disclosed
EP-0748247-A4 MACROCYCLIC ANTIBIOTICS AS SEPARATION AGENTS UNIV MISSOURI (US) 1998-05-06 EP disclosed
US-5626757-A RESOLUTION OF ENANTIOMORPHS BY ELECTROPHORESIS AND CHROMATOGRAPHY ADVANCED SEPARATION TECHNOLOGIES INC. (US) 1997-05-06 US disclosed
EP-0748247-A1 MACROCYCLIC ANTIBIOTICS AS SEPARATION AGENTS THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 1996-12-18 EP disclosed
US-5541633-A Ink jet printing of concealed images on carbonless paper XEROX CORPORATION (US) 1996-07-30 US disclosed
WO-1995022390-A1 MACROCYCLIC ANTIBIOTICS AS SEPARATION AGENTS CURATORS OF THE UNIVERSITY OF MISSOURI (US) 1995-08-24 WO disclosed
US-5286286-A Containing diethylene glycol monobutyl ether, glycerol, and a dansyl or porphyrin chromophores XEROX CORPORATION (US) 1994-02-15 US disclosed
US-4540548-A Method of detecting fluorescent materials and apparatus for their detection YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1985-09-10 US disclosed
US-4419452-A Method of detecting fluorescent materials and apparatus for their detection YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1983-12-06 US disclosed