Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.53 |
| ▸ | P4HB | P07237 | 11/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4120811 | 1.00 | FBP1 (0.53) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4120803 | 1.00 | FBP1 (0.53) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1687910 | 0.82 | FBP1 (0.65) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL2774364 | 0.82 | FBP1 (0.65) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL27645174 | 0.81 | P4HB (0.48) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL27571094 | 0.79 | FBP1 (0.57) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL29368312 | 0.79 | FBP1 (0.57) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL12228190 | 0.79 | FBP1 (0.57) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9186668 | 0.79 | FBP1 (0.61) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL21574844 | 0.79 | FBP1 (0.61) | FBP1P4HBGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2017275-A1 | BENZISOXAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | NR1I2, NR1I3, NR0B1 | FBP1 2679/4885P4HB 3041/4885GRIN2D 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.