Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900614 | 0.91 | KDM1A (0.45) | KDM1ARCOR1LIG1SLC9A1PTGS2 | |
| Water SCHEMBL2458176 | 0.90 | KDM1A (0.44) | KDM1ARCOR1LIG1SLC9A1PTGS2 | |
| Hydrochloric Acid SCHEMBL29430083 | 0.90 | KDM1A (0.47) | KDM1ARCOR1LIG1SLC9A1PTGS2 | |
| SCHEMBL2401865 | 0.84 | KDM1A (0.46) | KDM1AMAOAMAOB | |
| SCHEMBL4133969 | 0.83 | KDM1A (0.44) | KDM1ARCOR1LIG1KCNH2MAOA | |
| SCHEMBL5683641 | 0.81 | OPRK1 (0.43) | KDM1ARCOR1LIG1SLC9A1KMT2A | |
| SCHEMBL29453536 | 0.81 | KDM1A (0.41) | KDM1ARCOR1LIG1SLC9A1PTGS2 | |
| SCHEMBL4134001 | 0.81 | KDM1A (0.47) | KDM1ARCOR1KCNN4 | |
| SCHEMBL8905787 | 0.81 | F2 (0.40) | — | |
| Hydrochloric Acid SCHEMBL8904395 | 0.80 | BLM (0.39) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203750-A1 | 5-HT2C Receptor Agonists as Anorectic Agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-08-13 | — | — | US | disclosed |
| WO-2007025144-A1 | 5-HT2C RECEPTOR AGONISTS AS ANORECTIC AGENTS | UNIVERSITY OF ILLINOIS - CHICAGO (US) | 2007-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203750-A1 | 5-HT2C Receptor Agonists as Anorectic Agents | HTR2C, HTR2A, HTR5A | KDM1A 3105/4885RCOR1 2462/4885LIG1 4800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.