SCHEMBL4135037

SCHEMBL4135037

C=C(C)C(=O)OCCCC(=O)CC(C)=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
THRB P10828 1/20 0.47
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KDM4E B2RXH2 1/20 0.41
KDM6B O15054 1/20 0.41
KDM5C P41229 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
PHF8 Q9UPP1 1/20 0.41
KDM2A Q9Y2K7 1/20 0.41
ALDH1A1 P00352 3/20 0.40
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15450833 0.95 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL608159 0.89 THRB (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL632252 0.87 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9160051 0.86 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28034640 0.84 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1436455 0.84 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL15655553 0.84 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL532367 0.84 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL255879 0.84 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL25339939 0.83 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090294876-A1 METHOD FOR DEPOSITION OF AN ULTRA-THIN ELECTROPOSITIVE METAL-CONTAINING CAP LAYER INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-12-03 US disclosed
US-20090008725-A1 METHOD FOR DEPOSITION OF AN ULTRA-THIN ELECTROPOSITIVE METAL-CONTAINING CAP LAYER INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-01-08 US disclosed
US-6540974-B2 Process for making mixed metal oxides AGERE SYSTEMS INC. 2003-04-01 US disclosed
US-20010040785-A1 Thin film deposition of mixed metal oxides HILCO PATENT ACQUISITION 56, LLC 2001-11-15 US disclosed
US-6312565-B1 Thin film deposition of mixed metal oxides AGERE SYSTEMS GUARDIAN CORP. 2001-11-06 US disclosed