Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | RAB9A | P51151 | 1/20 | 0.81 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.81 |
| ▸ | FLT3 | P36888 | 6/20 | 0.75 |
| ▸ | TSHR | P16473 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | GFER | P55789 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3125764 | 0.94 | ALDH1A1 (0.88) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8288697 | 0.92 | ALDH1A1 (0.86) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL5457782 | 0.92 | ALDH1A1 (0.95) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL5804235 | 0.91 | HPGD (0.71) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL5804228 | 0.91 | HPGD (0.71) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8288672 | 0.91 | ALDH1A1 (0.93) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8288688 | 0.90 | ALDH1A1 (0.91) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8289669 | 0.90 | HPGD (0.76) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL5465217 | 0.89 | ALDH1A1 (0.81) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL5455950 | 0.89 | HPGD (0.83) | HPGDLMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143411-A1 | Thiophens and Their Use as Anti-Tumor Agents | COMPASS PHARMACEUTICALS LLC (US) | 2009-06-04 | — | — | US | claimed |
| US-20090143411-A1 | Thiophens and Their Use as Anti-Tumor Agents | COMPASS PHARMACEUTICALS LLC (US) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143411-A1 | Thiophens and Their Use as Anti-Tumor Agents | TP53, BRDT, VHL | HPGD 2732/4885LMNA 3634/4885ALDH1A1 1202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.