Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10975798 | 0.81 | HTT (0.33) | HSD17B10SMN1; SMN2MAPTKDM4EMITF | |
| SCHEMBL11198611 | 0.78 | HSD17B10 (0.43) | HSD17B10SMN1; SMN2MAPTKDM4EEHMT2 | |
| SCHEMBL192228 | 0.77 | APOBEC3G (0.43) | HSD17B10HDAC8HSP90AA1SMN1; SMN2MAPT | |
| SCHEMBL17274043 | 0.77 | POLB (0.52) | SMN1; SMN2MAPTKDM4EAPOBEC3GHTT | |
| SCHEMBL2129184 | 0.76 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2MAPTKDM4EEHMT2 | |
| SCHEMBL12804177 | 0.74 | EHMT2 (0.61) | HSD17B10SMN1; SMN2MAPTKDM4EEHMT2 | |
| SCHEMBL1275151 | 0.73 | KDM4E (0.36) | HSD17B10HSP90AA1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL10396004 | 0.73 | CYP3A4 (0.59) | HSP90AA1MAPTKDM4EMAPK1CYP1A2 | |
| SCHEMBL7838204 | 0.72 | — | — | |
| SCHEMBL11319203 | 0.72 | EHMT2 (0.39) | HSD17B10HDAC8HSP90AA1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025103355-A1 | ANTI-EGFR AND -HER3 BISPECIFIC ANTIBODY-DRUG CONJUGATE AND USE THEREOF | 信达生物制药(苏州)有限公司 | 2025-05-22 | — | — | WO | claimed |
| WO-2025103355-A1 | ANTI-EGFR AND -HER3 BISPECIFIC ANTIBODY-DRUG CONJUGATE AND USE THEREOF | 信达生物制药(苏州)有限公司 | 2025-05-22 | — | — | WO | disclosed |
| CN-105218418-A | A kind of preparation method of thioether | UNIV YICHUN | 2016-01-06 | — | — | CN | disclosed |
| US-8673885-B1 | Compounds for the protection of sulfur containing linkers in nucleic acid synthesis | DUFF ROBERT (US) | 2014-03-18 | — | — | US | disclosed |
| US-20090061460-A1 | TEST APPARATUS, PRODUCTION METHOD THEREFOR AND TEST METHOD | ANALYTICON BIOTECHNOLOGIES AG (DE) | 2009-03-05 | — | — | US | disclosed |
| EP-0124630-B1 | PYRIMIDINETHIOALKYL PYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | LUDWIG HEUMANN & CO GMBH (DE) | 1987-01-28 | — | — | EP | disclosed |