SCHEMBL4135913

SCHEMBL4135913

O=C(O)CCC(CP(=O)(O)CC(CCC(=O)O)C(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM3 Q14832 2/20 1.00
FOLH1 Q04609 7/20 0.77
NAALAD2 Q9Y3Q0 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5060080 0.92 GRM3 (0.85) GRM3FOLH1NAALAD2
SCHEMBL4143572 0.91 GRM3 (0.82) GRM3FOLH1NAALAD2
SCHEMBL5060255 0.91 GRM3 (0.82) GRM3FOLH1NAALAD2
SCHEMBL18647063 0.91 GRM3 (0.82) GRM3FOLH1NAALAD2
SCHEMBL5051325 0.90 GRM3 (0.81) GRM3FOLH1NAALAD2
SCHEMBL20529841 0.90 GRM3 (0.81) GRM3FOLH1NAALAD2
SCHEMBL5053371 0.89 GRM3 (0.79) GRM3FOLH1NAALAD2
SCHEMBL1376163 0.88 GRM3 (0.79) GRM3FOLH1NAALAD2
SCHEMBL1377500 0.88 GRM3 (0.79) GRM3FOLH1NAALAD2
SCHEMBL16528703 0.87 FOLH1 (1.00) GRM3FOLH1NAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3893028-B1 METHOD FOR SECURITY INSPECTION AND KIT OF PARTS WITH A DETACHABLE SINGLE-USE INLAY FOR AN X-RAY TRAY GONZALEZ MARIN SARAY (DE) 2025-06-04 EP claimed
CN-119977917-A Chemically responsive crosslinking agent and preparation method and application thereof 南开大学 2025-05-13 CN claimed
CN-119371639-A Preparation method of one-dimensional graphite alkyne chain 昆明理工大学 2025-01-28 CN claimed
CN-117924725-A Crystalline semiconductor material, preparation method thereof and application thereof in radiation detection and imaging field 闽都创新实验室 2024-04-26 CN claimed
CN-114805653-B Phenyl polydiacetylenic acid and preparation method, application and recovery thereof 常州大学 2023-06-20 CN claimed
CN-112812353-B Flexible colorless transparent polyimide composite structure and preparation method thereof 长春聚明光电材料有限公司 2023-04-28 CN claimed
CN-114805653-A Phenyl polydiacetylene acid and preparation method, application and recovery thereof 常州大学 2022-07-29 CN claimed
US-10730998-B2 Bio-based thermosets NDSU RESEARCH FOUNDATION (US) 2020-08-04 US claimed
US-20180244834-A1 BIO-BASED THERMOSETS NDSU RESEARCH FOUNDATION 2018-08-30 US claimed
WO-2017048949-A1 BIO-BASED THERMOSETS NDSU RESEARCH FOUNDATION (US) 2017-03-23 WO claimed
US-12582612-B2 Pharmaceutical composition of Siglec-binding agents CYTODIGM, INC. (US) 2026-03-24 US disclosed
US-20260000700-A1 TARGETED LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME TARGIMMUNE THERAPEUTICS AG (CH) 2026-01-01 US disclosed
US-20260000771-A1 PSMA-TARGETING LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME TARGIMMUNE THERAPEUTICS AG (CH) 2026-01-01 US disclosed
WO-2025238236-A1 POLYPLEXES OF NUCLEIC ACIDS AND TARGETED CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL TARGIMMUNE THERAPEUTICS AG (CH) 2025-11-20 WO disclosed
CN-119977917-B Chemically responsive crosslinking agent and preparation method and application thereof 南开大学 2025-11-18 CN disclosed
US-20040054190-A1 Imaging prostate cancer JOHNS HOPKINS UNIVERSITY 2004-03-18 US disclosed
US-20040002478-A1 Ligands for metabotropic glutamate receptors and inhibitors of NAALADase NIH - DEITR 2004-01-01 US disclosed
WO-2003060523-A1 IMAGING AGENTS AND METHODS OF IMAGING NAALADASE OF PSMA JOHNS HOPKINS UNIVERSITY (US) 2003-07-24 WO disclosed
US-6528499-B1 Ligands for metabotropic glutamate receptors and inhibitors of NAALADase GEORGETOWN UNIVERSITY 2003-03-04 US disclosed
WO-2002022627-A2 LIGANDS FOR METABOTROPIC GLUTAMATE RECEPTORS GEORGETWON UNIVERSITY (US) 2002-03-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040054190-A1 Imaging prostate cancer FOLH1, DUT, NAALAD2 GRM3 3266/4885FOLH1 1/4885NAALAD2 3/4885
US-20260000771-A1 PSMA-TARGETING LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME PSMA1, PSMA3, PSMA2 GRM3 616/4885FOLH1 9/4885NAALAD2 419/4885
US-20040002478-A1 Ligands for metabotropic glutamate receptors and inhibitors of NAALADase GRM3, GRM2, GRM1 GRM3 1/4885FOLH1 167/4885NAALAD2 52/4885
US-20260000700-A1 TARGETED LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME CTDSP1, POLM, MCTS1 GRM3 1575/4885FOLH1 1294/4885NAALAD2 3059/4885
US-12582612-B2 Pharmaceutical composition of Siglec-binding agents SIGLEC7, SIGLEC9, CD2 GRM3 2802/4885FOLH1 1488/4885NAALAD2 1847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.