Edetic Acid

Edetic Acid

SCHEMBL413599

N.N.O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O.[Cu]

nearest known ligand 0.88

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.88
EYA2 O00167 1/20 0.88
APP P05067 1/20 0.88
ACE P12821 1/20 0.88
BLM P54132 2/20 0.82
PMP22 Q01453 2/20 0.82
KDM4E B2RXH2 2/20 0.82
ALOX15 P16050 2/20 0.82
TSHR P16473 2/20 0.82
LMNA P02545 1/20 0.82
CHRM2 P08172 1/20 0.82
ADRA2A P08913 1/20 0.82
DRD1 P21728 1/20 0.82
SLC6A2 P23975 1/20 0.82
SLC6A4 P31645 1/20 0.82
CYP2C19 P33261 1/20 0.82
ADRA1A P35348 1/20 0.82
DRD3 P35462 1/20 0.82
SLC6A3 Q01959 1/20 0.82
HRH3 Q9Y5N1 1/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Edetic Acid SCHEMBL1079425 0.97 TDP1 (0.93) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL119008 0.97 TDP1 (0.93) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL602070 0.97 TDP1 (0.93) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL394052 0.97 TDP1 (0.93) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL17097349 0.97 TDP1 (0.93) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL3735469 0.97 TDP1 (0.93) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL1832119 0.97 TDP1 (0.93) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL144662 0.97 TDP1 (0.93) TDP1EYA2APPACEBLM
Pentetic Acid SCHEMBL11041213 0.94 TDP1 (0.94) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL2334729 0.94 TDP1 (0.88) TDP1EYA2APPACEBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8715745-B2 Fungicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES, LLC. (US) 2014-05-06 US claimed
US-8563472-B2 Synergistic fungicidal and algicidal compositions including 2-hydroxyphenylaldehyde and 2-hydroxyphenylketone heterocycloyhydrazones and copper DOW AGROSCIENCES, LLC. (US) 2013-10-22 US claimed
US-8476194-B2 Fungicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES, LLC (US) 2013-07-02 US claimed
EP-2605653-A1 SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER Dow AgroSciences LLC (US) 2013-06-26 EP claimed
EP-2605651-A1 SYNERGISTIC FUNGICIDAL AND ALGICIDAL COMPOSITIONS INCLUDING 2-HYDROXYPHENYLALDEHYDE AND 2-HYDROXYPHENYLKETONE HETEROCYCLOYLHYDRAZONES AND COPPER Dow AgroSciences LLC (US) 2013-06-26 EP claimed
EP-2605660-A2 SYNERGISTIC FUNGICIDAL AND ALGICIDAL COMPOSITIONS INCLUDING 7-HYDROXY-INDANONE BENZOYLHYDRAZONES AND COPPER Dow AgroSciences LLC (US) 2013-06-26 EP claimed
US-8461078-B2 Fungicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES LLC (US) 2013-06-11 US claimed
US-8455394-B2 Fungicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES, LLC (US) 2013-06-04 US claimed
US-20120148682-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-06-14 US claimed
US-20120141597-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-06-07 US claimed
EP-2376441-A2 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER Dow AgroSciences LLC (US) 2011-10-19 EP claimed
EP-2376436-A2 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER Dow AgroSciences LLC (US) 2011-10-19 EP claimed
EP-2376438-A2 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER Dow AgroSciences LLC (US) 2011-10-19 EP claimed
WO-2010083318-A2 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2010-07-22 WO claimed
WO-2010083322-A2 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2010-07-22 WO claimed
WO-2010083307-A2 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2010-07-22 WO claimed
WO-2010083319-A2 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2010-07-22 WO claimed
WO-2010083310-A2 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2010-07-22 WO claimed
WO-2010083316-A2 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2010-07-22 WO claimed
WO-2010083314-A2 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2010-07-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120148682-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER SOD1, CYP51A1, CYP4Z1 TDP1 2868/4885EYA2 1509/4885APP 2600/4885
US-20120141597-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER SOD1, CYP51A1, CYP4Z1 TDP1 2868/4885EYA2 1509/4885APP 2600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.