SCHEMBL4136194

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4148920	0.86	TTK (0.53)	TTKALDH1A1POLBSMN1; SMN2KMT2A
	SCHEMBL2861507	0.80	TTK (0.47)	TTKALDH1A1POLBSMN1; SMN2KMT2A
	SCHEMBL2868770	0.79	AURKA (0.51)	TTKALDH1A1POLBSMN1; SMN2KMT2A
	SCHEMBL4136721	0.79	MAPK8 (0.50)	TTKNPC1RAB9AMAPK1AURKB
	SCHEMBL2866649	0.78	USP2 (0.48)	TTKALDH1A1POLBSMN1; SMN2KMT2A
	SCHEMBL14074986	0.77	GSK3B (0.56)	NPC1RAB9AMAPK8MAPK9GSK3B
	SCHEMBL2860243	0.76	TTK (0.50)	TTKALDH1A1POLBSMN1; SMN2KMT2A
	SCHEMBL6426161	0.75	ADORA3 (0.54)	ALDH1A1POLBSMN1; SMN2KMT2AMEN1
	SCHEMBL4041685	0.72	POLB (0.62)	ALDH1A1POLBSMN1; SMN2KMT2AMEN1
	SCHEMBL4148946	0.72	AURKA (0.53)	ALDH1A1POLBSMN1; SMN2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.