Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 10/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | ESR1 | P03372 | 3/20 | 0.54 |
| ▸ | GAPDH | P04406 | 2/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931752 | 0.78 | KMT2A (0.49) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4034766 | 0.76 | NLRP3 (0.51) | SMN1; SMN2KMT2AMAPTALOX15TDP1 | |
| SCHEMBL4037192 | 0.75 | LMNA (0.56) | POLBALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL9311156 | 0.73 | KDM4E (0.57) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4136194 | 0.72 | TTK (0.49) | POLBALDH1A1SMN1; SMN2ESR1GAPDH | |
| SCHEMBL8340280 | 0.72 | KDM4E (0.51) | ALDH1A1SMN1; SMN2KMT2AHSD17B10HPGD | |
| SCHEMBL3416441 | 0.72 | POLB (0.60) | POLBALDH1A1SMN1; SMN2ESR1GAPDH | |
| SCHEMBL7195570 | 0.72 | KMT2A (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL4040914 | 0.70 | KMT2A (0.45) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6122009 | 0.70 | TSHR (0.56) | POLBALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | disclosed |