Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29259785 | 0.82 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL2881016 | 0.78 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL2875881 | 0.77 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2POLBNSD2 | |
| SCHEMBL29260038 | 0.75 | AKR1C3 (0.69) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL30822634 | 0.75 | AKR1C3 (0.69) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL7113122 | 0.74 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL29259796 | 0.74 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL10589292 | 0.74 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL9577185 | 0.73 | RECQL (0.74) | ALDH1A1SMN1; SMN2POLBCA12CA9 | |
| SCHEMBL15915771 | 0.71 | RECQL (0.59) | ALDH1A1SMN1; SMN2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066628-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | Sanofi-Aventis (FR) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008014186-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | SANOFI-AVENTIS (FR) | 2008-01-31 | — | — | WO | disclosed |