Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6393658 | 0.98 | MTNR1A (0.49) | MTNR1AMTNR1BESR1MAPTTP53 | |
| SCHEMBL245816 | 0.96 | MTNR1A (0.51) | MTNR1AMTNR1BESR1MAPTTP53 | |
| Water SCHEMBL28663040 | 0.95 | MTNR1A (0.50) | MTNR1AMTNR1BESR1MAPTTP53 | |
| SCHEMBL309045 | 0.95 | MTNR1A (0.50) | MTNR1AMTNR1BESR1MAPTTP53 | |
| SCHEMBL17685579 | 0.95 | ESR1 (0.51) | MTNR1AMTNR1BESR1MAPTTP53 | |
| Water SCHEMBL20853630 | 0.94 | MTNR1A (0.49) | MTNR1AMTNR1BESR1MAPTTP53 | |
| SCHEMBL5522288 | 0.94 | MTNR1A (0.49) | MTNR1AMTNR1BESR1MAPTTP53 | |
| SCHEMBL20853803 | 0.91 | MAPT (0.43) | MTNR1AMTNR1BESR1MAPTTP53 | |
| SCHEMBL25118360 | 0.90 | MTNR1B (0.57) | MTNR1AMTNR1BESR1ALDH1A1ALOX15 | |
| SCHEMBL30060301 | 0.90 | MTNR1B (0.57) | MTNR1AMTNR1BESR1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090226944-A1 | METHOD FOR MEASURING TRIGLYCERIDE IN LOW-DENSITY LIPOPROTEIN AND KIT FOR MEASUREMENT | KYOWA MEDEX CO., LTD. (JP) | 2009-09-10 | — | — | US | disclosed |
| EP-1953240-A1 | METHOD FOR MEASURING TRIGLYCERIDE IN LOW-DENSITY LIPOPROTEIN AND KIT FOR MEASUREMENT | Kyowa Medex Co., Ltd. (JP) | 2008-08-06 | — | — | EP | disclosed |