SCHEMBL4137029

SCHEMBL4137029

NC(=O)CC(Cl)(Cl)C(N)=O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
GLA P06280 1/20 0.33
POLB P06746 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
CYP2C19 P33261 1/20 0.33
THPO P40225 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL540840 0.75
SCHEMBL8968643 0.73
SCHEMBL3503450 0.73
SCHEMBL27591892 0.71
SCHEMBL10951689 0.71
SCHEMBL27802474 0.70 KMT2A (0.30) TP53CYP1A2CYP3A4ALOX15CYP2C19
SCHEMBL11002111 0.70
SCHEMBL7753480 0.69
SCHEMBL5962093 0.69 SMPD1 (0.32) TDP1
SCHEMBL29210021 0.67 ALDH1A1 (0.36) ALDH1A1LMNATP53ALOX15BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080299161-A1 Solid Biocide Composition and Sealed Biocide Article SANDERSON WILLIAM D 2008-12-04 US claimed
EP-1968380-A2 SOLID BIOCIDE COMPOSITION AND SEALED BIOCIDE ARTICLE Sanderson, William D. (US) 2008-09-17 EP claimed
US-7285522-B2 Adding to wash water a granule or tablet containing a hypohalite-generating compound, a bromide-releasing compound, a fluorescent whitener; increases the measured textile whitening performance versus a control by a Delta W value of greater than 3.0 THE CLOROX COMPANY (US) 2007-10-23 US claimed
WO-2007078838-A2 SOLID BIOCIDE COMPOSITION AND SEALED BIOCIDE ARTICLE SANDERSON WILLIAM D (US) 2007-07-12 WO claimed
WO-2006026048-A2 BLEACHING WITH IMPROVED WHITENING THE CLOROX COMPANY (US) 2006-03-09 WO claimed
US-20060046946-A1 Adding to wash water a granule or tablet containing a hypohalite-generating compound, a bromide-releasing compound, a fluorescent whitener; increases the measured textile whitening performance versus a control by a Delta W value of greater than 3.0 THE CLOROX COMPANY 2006-03-02 US claimed
US-20090232903-A1 BIOCIDE COMPOSITIONS SANDERSON WILLIAM D 2009-09-17 US disclosed
US-20080299161-A1 Solid Biocide Composition and Sealed Biocide Article SANDERSON WILLIAM D 2008-12-04 US disclosed
EP-1968380-A2 SOLID BIOCIDE COMPOSITION AND SEALED BIOCIDE ARTICLE Sanderson, William D. (US) 2008-09-17 EP disclosed
US-7285522-B2 Adding to wash water a granule or tablet containing a hypohalite-generating compound, a bromide-releasing compound, a fluorescent whitener; increases the measured textile whitening performance versus a control by a Delta W value of greater than 3.0 THE CLOROX COMPANY (US) 2007-10-23 US disclosed
WO-2007078838-A2 SOLID BIOCIDE COMPOSITION AND SEALED BIOCIDE ARTICLE SANDERSON WILLIAM D (US) 2007-07-12 WO disclosed
WO-2006026048-A2 BLEACHING WITH IMPROVED WHITENING THE CLOROX COMPANY (US) 2006-03-09 WO disclosed
US-20060046946-A1 Adding to wash water a granule or tablet containing a hypohalite-generating compound, a bromide-releasing compound, a fluorescent whitener; increases the measured textile whitening performance versus a control by a Delta W value of greater than 3.0 THE CLOROX COMPANY 2006-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090232903-A1 BIOCIDE COMPOSITIONS CAT, BLVRB, BLK KDM4E 4301/4885GMNN 2612/4885USP2 596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.