Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR2 | O95665 | 9/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 9/20 | 0.52 |
| ▸ | F2R | P25116 | 2/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.48 |
| ▸ | GRB2 | P62993 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL413760 | 1.00 | NTSR2 (0.52) | NTSR2NTSR1F2RSORT1F2 | |
| SCHEMBL32681278 | 0.93 | NTSR2 (0.52) | NTSR2NTSR1SORT1F2CAPN1 | |
| SCHEMBL30439138 | 0.93 | NTSR1 (0.55) | NTSR2NTSR1SORT1F2 | |
| SCHEMBL416859 | 0.93 | NTSR2 (0.49) | NTSR2NTSR1F2RSORT1F2 | |
| SCHEMBL416858 | 0.93 | NTSR2 (0.49) | NTSR2NTSR1F2RSORT1F2 | |
| SCHEMBL31401992 | 0.90 | NTSR1 (0.58) | NTSR2NTSR1SORT1 | |
| SCHEMBL30723553 | 0.90 | OPRM1 (0.53) | NTSR2NTSR1SORT1F2CAPN1 | |
| SCHEMBL29726629 | 0.89 | F2 (0.55) | NTSR2NTSR1SORT1F2GRB2 | |
| SCHEMBL29722113 | 0.89 | CAPN1 (0.54) | NTSR2NTSR1F2RSORT1CAPN1 | |
| Bromide SCHEMBL8603293 | 0.88 | F2 (0.54) | NTSR2NTSR1SORT1F2GRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120020878-A1 | FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2012-01-26 | — | — | US | claimed |
| US-20120020878-A1 | FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2012-01-26 | — | — | US | disclosed |