SCHEMBL4137908

SCHEMBL4137908

C=CC(=O)OCc1ccc(OC(=O)OC(C)(C)C)cc1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.51
THRB P10828 4/20 0.49
KDM1A O60341 1/20 0.40
HTR2A P28223 1/20 0.39
PDE6D O43924 1/20 0.36
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
CA2 P00918 1/20 0.34
THRA P10827 1/20 0.34
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
NR4A2 P43354 1/20 0.33
MAPKAPK2 P49137 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4143696 0.85 ELANE (0.64) ELANETHRBKDM1APDE6DCA2
SCHEMBL12284434 0.83 THRB (0.62) ELANETHRBHTR2APDE6DHPGD
SCHEMBL12895150 0.81 ELANE (0.56) ELANETHRBKDM1A
SCHEMBL8390062 0.81 THRB (0.55) ELANETHRBHPGDTSHRHCAR2
SCHEMBL690734 0.79 THRB (0.57) THRBHTR2APDE6DHPGDTSHR
SCHEMBL6274586 0.79 ELANE (0.64) ELANETHRBKDM1ACA2PPARG
SCHEMBL2556244 0.78 HCAR2 (0.50) THRBHPGDTSHRHCAR2
SCHEMBL2428833 0.77 ALDH1A1 (0.53) THRBTSHR
SCHEMBL196293 0.77 ELANE (0.66) ELANEKDM1ACA2PPARGPPARA
SCHEMBL10882382 0.77 THRB (0.49) THRBHPGDTSHRHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090130419-A1 FOAM SHEET AND PRODUCTION PROCESS THEREOF OJI PAPER CO., LTD (JP) 2009-05-21 US disclosed
US-20060210785-A1 Foamed product in a sheet form and method for production thereof OJI PAPER CO., LTD. (JP) 2006-09-21 US disclosed
EP-1647570-A1 FOAMED PRODUCT IN A SHEET FORM AND METHOD FOR PRODUCTION THEREOF Oji Paper Co., Ltd. (JP) 2006-04-19 EP disclosed