SCHEMBL4138134

SCHEMBL4138134

CCCCOC(=O)c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
ESR1 P03372 8/20 0.59
TSHR P16473 4/20 0.59
LMNA P02545 2/20 0.59
CYP1A2 P05177 2/20 0.59
CYP2C19 P33261 2/20 0.59
MAPK1 P28482 2/20 0.59
CYP2D6 P10635 1/20 0.59
NR1H2 P55055 1/20 0.59
RNASEL Q05823 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
CYP3A4 P08684 1/20 0.58
CYP2C9 P11712 1/20 0.58
PDE4D Q08499 1/20 0.58
L3MBTL1 Q9Y468 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
HPGD P15428 2/20 0.52
RECQL P46063 1/20 0.52
ALDH1A1 P00352 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27261457 0.95 TSHR (0.61) MEN1KMT2AESR1TSHRLMNA
SCHEMBL22289845 0.94 ALDH1A1 (0.60) MEN1KMT2AESR1TSHRLMNA
SCHEMBL27633236 0.94 ALDH1A1 (0.60) MEN1KMT2AESR1TSHRLMNA
SCHEMBL27543962 0.94 ALDH1A1 (0.60) MEN1KMT2AESR1TSHRLMNA
SCHEMBL4143411 0.94 ALDH1A1 (0.60) MEN1KMT2AESR1TSHRLMNA
SCHEMBL27393188 0.94 ALDH1A1 (0.60) MEN1KMT2AESR1TSHRLMNA
SCHEMBL12311685 0.90 LMNA (0.59) MEN1KMT2AESR1TSHRLMNA
SCHEMBL10425325 0.90 TSHR (0.63) MEN1KMT2AESR1TSHRLMNA
SCHEMBL28550408 0.90 TSHR (0.63) MEN1KMT2AESR1TSHRLMNA
SCHEMBL4731524 0.90 TSHR (0.54) MEN1KMT2AESR1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2059856-B1 ELECTROSTATIC IMAGE DEVELOPING TONER, TWO-COMPONENT DEVELOPER, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH CO LTD (JP) 2016-05-25 EP disclosed
US-8084179-B2 Electrostatic image developing toner having specific variation coefficient of number distribution, two-component developer, image forming method and process cartridge RICOH COMPANY, LTD. (JP) 2011-12-27 US disclosed
CN-102216387-A Method for producing composition of polymerizable organic compound containing silica particles NISSAN CHEMICAL IND LTD 2011-10-12 CN disclosed
US-20090202934-A1 ELECTROSTATIC IMAGE DEVELOPING TONER, TWO-COMPONENT DEVELOPER, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-08-13 US disclosed
EP-2059856-A1 ELECTROSTATIC IMAGE DEVELOPING TONER, TWO-COMPONENT DEVELOPER, IMAGE FORMING METHOD AND PROCESS CARTRIDGE Ricoh Company, Ltd. (JP) 2009-05-20 EP disclosed
WO-2008029863-A1 ELECTROSTATIC IMAGE DEVELOPING TONER, TWO-COMPONENT DEVELOPER, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-03-13 WO disclosed
US-7300736-B2 Toner, and developer, image forming method, image forming apparatus and process cartridge using the toner RICOH COMPANY, LTD. (JP) 2007-11-27 US disclosed
US-20070264035-A1 TONER, AND DEVELOPER, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE TONER FUSHIMI HIROYUKI 2007-11-15 US disclosed
EP-1248158-B1 Toner, developer, and image forming method and apparatus RICOH KK (JP) 2006-06-07 EP disclosed
US-6916587-B2 Toner, developer, and image forming method and apparatus RICOH COMPANY LIMITED (JP) 2005-07-12 US disclosed
US-20050003289-A1 Toner, and developer, image forming method, image forming apparatus and process cartridge using the toner RICOH COMPANY, LTD. (JP) 2005-01-06 US disclosed
EP-1482380-A1 Toner and developer, image forming method, image forming apparatus and process cartridge using the toner Ricoh Company (JP) 2004-12-01 EP disclosed
EP-1248158-A1 Toner, developer, and image forming method and apparatus Ricoh Company, Ltd. (JP) 2002-10-09 EP disclosed