Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494974 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1L3MBTL1CYP1A2CYP3A4 | |
| Dichlobenil SCHEMBL55606 | 0.81 | ALDH1A1 (0.55) | KDM4EALDH1A1L3MBTL1CYP1A2CYP3A4 | |
| Dichlobenil SCHEMBL1701380 | 0.81 | ALDH1A1 (0.55) | KDM4EALDH1A1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL8779801 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL11326735 | 0.79 | MAOA (0.44) | KDM4EALDH1A1L3MBTL1CYP1A2CYP3A4 | |
| Dichlobenil SCHEMBL10737856 | 0.79 | ALDH1A1 (0.53) | KDM4EALDH1A1L3MBTL1CYP1A2CYP3A4 | |
| Dichlobenil SCHEMBL28232070 | 0.79 | ALDH1A1 (0.53) | KDM4EALDH1A1L3MBTL1CYP1A2CYP3A4 | |
| Dichlobenil SCHEMBL10741379 | 0.77 | ALDH1A1 (0.52) | KDM4EALDH1A1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL9129444 | 0.76 | CYP1A2 (0.57) | KDM4EALDH1A1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL3458187 | 0.76 | CYP1A2 (0.42) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069317-A1 | Insecticidal Methods Using 3-Amino-1,2-Benzisothiazole Derivatives | BASF SE (DE) | 2009-03-12 | — | — | US | disclosed |
| EP-1954138-A2 | INSECTICIDAL METHODS USING 3-AMINO-1,2-BENZISOTHIAZOLE DERIVATIVES | BASF SE (DE) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007057407-A2 | INSECTICIDAL METHODS USING 3-AMINO-1,2-BENZISOTHIAZOLE DERIVATIVES | BASF SE (DE) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069317-A1 | Insecticidal Methods Using 3-Amino-1,2-Benzisothiazole Derivatives | AAAS, API5, ATL3 | KDM4E 1247/4885ALDH1A1 731/4885L3MBTL1 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.