Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.58 |
| ▸ | L3MBTL3 | Q96JM7 | 12/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 10/20 | 0.53 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.52 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.52 |
| ▸ | L3MBTL4 | Q8NA19 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4930102 | 0.86 | HRH3 (0.75) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL4938741 | 0.84 | HRH3 (0.58) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL590136 | 0.81 | L3MBTL3 (0.79) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL4147049 | 0.79 | L3MBTL3 (0.67) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL4130681 | 0.78 | L3MBTL3 (0.66) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL4139958 | 0.78 | L3MBTL3 (0.66) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL4134784 | 0.76 | L3MBTL3 (0.60) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL4136891 | 0.75 | L3MBTL3 (0.62) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL4282496 | 0.75 | L3MBTL3 (0.58) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL743038 | 0.74 | HPGD (0.63) | L3MBTL3POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021004-A2 | SUBSTITUTED AZASPIRO DERIVATIVES | NEUROGEN CORPORATION (US) | 2009-02-11 | — | — | EP | claimed |
| WO-2007133561-A2 | SUBSTITUTED AZASPIRO DERIVATIVES | NEUROGEN CORPORATION (US) | 2007-11-22 | — | — | WO | claimed |