Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4146649 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTTDP1CHEK1 | |
| SCHEMBL4134606 | 0.80 | KDM4E (0.48) | ALDH1A1KDM4EMAPTTDP1CHEK1 | |
| SCHEMBL4131819 | 0.76 | KDM4E (0.47) | ALDH1A1KDM4EMAPTTDP1CHEK1 | |
| Hydrochloric Acid SCHEMBL4134795 | 0.76 | KDM4E (0.43) | ALDH1A1KDM4EMAPTTDP1CHEK1 | |
| SCHEMBL4139197 | 0.73 | KDM4E (0.43) | ALDH1A1KDM4EMAPTTDP1CHEK1 | |
| SCHEMBL30932453 | 0.71 | KDM4E (0.51) | ALDH1A1KDM4EMAPTTDP1CHEK1 | |
| SCHEMBL4139069 | 0.71 | KDM4E (0.42) | ALDH1A1KDM4EMAPTTDP1CHEK1 | |
| SCHEMBL29229082 | 0.71 | KDM4E (0.63) | ALDH1A1KDM4EMAPTTDP1CHEK1 | |
| SCHEMBL11534549 | 0.67 | KDM4E (1.00) | ALDH1A1KDM4EMAPTTDP1CHEK1 | |
| SCHEMBL9517014 | 0.65 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTTDP1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090093476-A1 | PYRROLO[1,2-A]QUINOXALINE DERIVATIVES AS ADENOSINE A3 RECEPTOR MODULATORS AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2009-04-09 | — | — | US | disclosed |
| EP-1798233-A1 | Pyrrolo[1,2-a]quinoxaline derivatives as Adenosine A3 receptor modulators and uses thereof | Faust Pharmaceuticals (FR) | 2007-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093476-A1 | PYRROLO[1,2-A]QUINOXALINE DERIVATIVES AS ADENOSINE A3 RECEPTOR MODULATORS AND USES THEREOF | ADORA3, ADORA2A, ADORA1 | ALDH1A1 1300/4885KDM4E 3489/4885MAPT 4584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.