Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858521 | 0.78 | ELANE (0.44) | ELANETOP1FBP1CA2CA9 | |
| SCHEMBL4139429 | 0.78 | CA9 (0.36) | ELANETOP1CA2CA9MEN1 | |
| SCHEMBL3952641 | 0.75 | ELANE (0.52) | ELANETOP1FBP1ALDH1A1MAPT | |
| SCHEMBL7278505 | 0.75 | ELANE (0.53) | ELANECA12TDP1HTR2A | |
| SCHEMBL3947295 | 0.72 | HTT (0.45) | ELANEMEN1KMT2AMAPTLMNA | |
| SCHEMBL6990377 | 0.71 | CA12 (0.58) | ELANECA2CA9CA1CA12 | |
| SCHEMBL8668867 | 0.71 | DRD2 (0.49) | ELANECA9CA12HTR2A | |
| SCHEMBL8550940 | 0.70 | CA9 (0.59) | ELANECA2CA9KMT2ACA1 | |
| SCHEMBL7288998 | 0.69 | ELANE (0.66) | ELANE | |
| SCHEMBL19834255 | 0.69 | CA12 (0.52) | ELANECA9ALDH1A1CA12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069317-A1 | Insecticidal Methods Using 3-Amino-1,2-Benzisothiazole Derivatives | BASF SE (DE) | 2009-03-12 | — | — | US | disclosed |
| EP-1954138-A2 | INSECTICIDAL METHODS USING 3-AMINO-1,2-BENZISOTHIAZOLE DERIVATIVES | BASF SE (DE) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007057407-A2 | INSECTICIDAL METHODS USING 3-AMINO-1,2-BENZISOTHIAZOLE DERIVATIVES | BASF SE (DE) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069317-A1 | Insecticidal Methods Using 3-Amino-1,2-Benzisothiazole Derivatives | AAAS, API5, ATL3 | ELANE 2006/4885TOP1 1659/4885FBP1 1684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.