Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952641 | 0.89 | ELANE (0.52) | MAPTGAAELANELMNAHPGD | |
| SCHEMBL3947691 | 0.85 | HTT (0.44) | HTTMAPTGAAMEN1KMT2A | |
| SCHEMBL9858521 | 0.75 | ELANE (0.44) | HTTMAPTGAAMEN1KMT2A | |
| SCHEMBL4139401 | 0.72 | ELANE (0.42) | HTTMAPTMEN1KMT2AELANE | |
| SCHEMBL7278505 | 0.71 | ELANE (0.53) | GAAELANEHTR1ADRD2 | |
| SCHEMBL3955197 | 0.69 | MAPT (0.41) | HTTMAPTMEN1KMT2ALMNA | |
| SCHEMBL6990377 | 0.69 | CA12 (0.58) | ELANENPC1RAB9APAX8MAPK1 | |
| SCHEMBL8668867 | 0.68 | DRD2 (0.49) | ELANEHTR1ADRD2 | |
| SCHEMBL6358558 | 0.67 | CA12 (0.53) | HTTMAPTKMT2ALMNAHPGD | |
| SCHEMBL7288998 | 0.66 | ELANE (0.66) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655290-B1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | OREAL (FR) | 2009-04-29 | — | — | EP | claimed |
| US-7232839-B2 | Benzoisothiazolone compositions | L'OREAL (FR) | 2007-06-19 | — | — | US | claimed |
| US-20060142587-A1 | Benzoisothiazolone compositions | L'OREAL (FR) | 2006-06-29 | — | — | US | claimed |
| EP-1655290-A1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | L'OREAL (FR) | 2006-05-10 | — | — | EP | claimed |
| EP-1655290-B1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | OREAL (FR) | 2009-04-29 | — | — | EP | disclosed |
| EP-1655290-B1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | OREAL (FR) | 2009-04-29 | — | — | EP | disclosed |
| US-7232839-B2 | Benzoisothiazolone compositions | L'OREAL (FR) | 2007-06-19 | — | — | US | disclosed |
| US-7232839-B2 | Benzoisothiazolone compositions | L'OREAL (FR) | 2007-06-19 | — | — | US | disclosed |
| US-7232839-B2 | Benzoisothiazolone compositions | L'OREAL (FR) | 2007-06-19 | — | — | US | disclosed |
| US-20060142587-A1 | Benzoisothiazolone compositions | L'OREAL (FR) | 2006-06-29 | — | — | US | disclosed |
| EP-1655290-A1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | L'OREAL (FR) | 2006-05-10 | — | — | EP | disclosed |
| EP-1655290-A1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | L'OREAL (FR) | 2006-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142587-A1 | Benzoisothiazolone compositions | COL1A1, TYR, CUTA | HTT 4039/4885MAPT 597/4885GAA 3744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.