SCHEMBL4139931

SCHEMBL4139931

C=CC(=O)Oc1ccc(NC(=O)OC(C)(C)C)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 1/20 0.49
PPARG P37231 1/20 0.46
PPARA Q07869 1/20 0.46
TGM2 P21980 2/20 0.46
CYP17A1 P05093 2/20 0.46
THRB P10828 3/20 0.45
PSMB8 P28062 1/20 0.44
NAMPT P43490 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
ALDH1A1 P00352 3/20 0.42
GAA P10253 3/20 0.42
MAPT P10636 2/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18353040 0.88 LIPE (0.51) LIPEPPARGPPARACYP17A1THRB
SCHEMBL18354928 0.84 LIPE (0.48) LIPEPPARGPPARACYP17A1PSMB8
SCHEMBL7139404 0.83 TGM2 (0.59) TGM2CYP17A1THRBPSMB8NAMPT
SCHEMBL1162988 0.83 LIPE (0.52) LIPEPPARGPPARACYP17A1PSMB8
SCHEMBL6665914 0.83 LIPE (0.52) LIPEPPARGPPARACYP17A1THRB
SCHEMBL4636496 0.83 LIPE (0.52) LIPEPPARGPPARACYP17A1THRB
SCHEMBL13055402 0.82 CYP17A1 (0.59) LIPECYP17A1PSMB8NAMPTALDH1A1
SCHEMBL8834653 0.81 LIPE (0.48) LIPEPPARGPPARACYP17A1THRB
SCHEMBL29131710 0.80 HPGD (0.59) LIPEPPARGPPARACYP17A1PSMB8
SCHEMBL4143456 0.80 CYP17A1 (0.51) PPARGPPARATGM2CYP17A1PSMB8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090130419-A1 FOAM SHEET AND PRODUCTION PROCESS THEREOF OJI PAPER CO., LTD (JP) 2009-05-21 US disclosed
US-20060210785-A1 Foamed product in a sheet form and method for production thereof OJI PAPER CO., LTD. (JP) 2006-09-21 US disclosed
EP-1647570-A1 FOAMED PRODUCT IN A SHEET FORM AND METHOD FOR PRODUCTION THEREOF Oji Paper Co., Ltd. (JP) 2006-04-19 EP disclosed