Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4141257 | 0.92 | CCR1 (0.41) | TRPV4CCR1BMP1ADAM17GAA | |
| SCHEMBL5435367 | 0.91 | BMP1 (0.40) | TRPV4CCR1BMP1ADAM17ALDH1A1 | |
| SCHEMBL4130362 | 0.91 | POLB (0.34) | CCR1BMP1ADAM17CCR2ALDH1A1 | |
| SCHEMBL4145546 | 0.90 | CCR1 (0.35) | TRPV4CCR1BMP1ADAM17GAA | |
| SCHEMBL4141037 | 0.88 | BMP1 (0.37) | TRPV4CCR1BMP1ADAM17MCL1 | |
| SCHEMBL5439390 | 0.84 | BMP1 (0.36) | TRPV4CCR1BMP1ADAM17CCR2 | |
| SCHEMBL4130817 | 0.83 | CCR1 (0.38) | CCR1BMP1ADAM17ALDH1A1 | |
| SCHEMBL4140995 | 0.82 | CCR1 (0.38) | CCR1BMP1ADAM17ALDH1A1 | |
| SCHEMBL4136278 | 0.82 | BMP1 (0.39) | TRPV4CCR1BMP1ADAM17GAA | |
| SCHEMBL5439621 | 0.82 | CCR1 (0.38) | TRPV4CCR1BMP1ADAM17GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | SMITHKLINE BEECHAM CORPORATION | 2009-04-23 | — | — | US | claimed |
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | SMITHKLINE BEECHAM CORPORATION | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | TRPV4, TRPC4, TRPV1 | TRPV4 1/4885CCR1 766/4885BMP1 2172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.