Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639866 | 0.98 | DNM1 (0.50) | DNM1EPHX1NAAAHTTCES2 | |
| SCHEMBL7673548 | 0.91 | CA1 (0.43) | DNM1EPHX1LMNANPC1MAPT | |
| SCHEMBL1656553 | 0.91 | DNM1 (0.40) | DNM1EPHX1NAAAHTTNPC1 | |
| SCHEMBL9322459 | 0.85 | DNM1 (0.50) | DNM1EPHX1NAAACES2LMNA | |
| Furan SCHEMBL27720855 | 0.84 | DNM1 (0.40) | DNM1EPHX1LMNANPC1MAPT | |
| SCHEMBL6580840 | 0.83 | DNM1 (0.48) | DNM1NAAACES2MAPTTSHR | |
| SCHEMBL7784786 | 0.83 | DNM1 (0.48) | DNM1NAAACES2MAPTTSHR | |
| SCHEMBL9689014 | 0.83 | DNM1 (0.48) | DNM1NAAACES2MAPTTSHR | |
| SCHEMBL9508153 | 0.83 | DNM1 (0.48) | DNM1NAAACES2MAPTTSHR | |
| SCHEMBL11760703 | 0.83 | DNM1 (0.48) | DNM1NAAACES2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | TOUCH BIONICS LIMITED (GB) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | PGLS, TFPI, Q6ZSR9 | DNM1 371/4885EPHX1 4403/4885NAAA 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.