SCHEMBL414249

SCHEMBL414249

O=C(O)[C@]1(Cc2ccccc2)CCCN1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 7/20 0.56
SLC6A4 P31645 7/20 0.56
SLC6A3 Q01959 7/20 0.56
HRH3 Q9Y5N1 4/20 0.54
ARG1 P05089 1/20 0.45
ARG2 P78540 1/20 0.45
PARP1 P09874 1/20 0.41
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
CYP2D6 P10635 4/20 0.38
KCNH2 Q12809 2/20 0.38
AKR1C1 Q04828 1/20 0.37
ALDH1A1 P00352 1/20 0.37
ADRB2 P07550 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL440476 1.00 SLC6A2 (0.56) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL10956783 1.00 SLC6A2 (0.56) SLC6A2SLC6A4SLC6A3HRH3ARG1
Hydrochloric Acid SCHEMBL7375378 0.98 SLC6A2 (0.55) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL7455945 0.95 SLC6A2 (0.52) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL8083651 0.95 SLC6A2 (0.52) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL1819249 0.91 SLC6A2 (0.49) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL1052527 0.87 SLC6A2 (0.54) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL14828670 0.87 SLC6A2 (0.54) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL1052525 0.87 SLC6A2 (0.54) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL11234764 0.87 HRH3 (0.56) SLC6A2SLC6A4SLC6A3HRH3ARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3914068-A1 COMPOSITIONS FOR TREATING CITRUS DISEASE AND PROMOTING YIELD INCREASE IN ROW CROPS Spogen Biotech Inc. (US) 2021-12-01 EP claimed
CN-113395898-A Compositions for treating citrus disease and promoting yield enhancement of row crops 斯波根生物技术公司 2021-09-14 CN claimed
WO-2020154387-A1 COMPOSITIONS FOR TREATING CITRUS DISEASE AND PROMOTING YIELD INCREASE IN ROW CROPS SPOGEN BIOTECH INC. (US) 2020-07-30 WO claimed
EP-3606347-A1 AGRICULTURAL COMPOSITIONS FOR IMPROVED CROP PRODUCTIVITY AND ENHANCED PHENOTYPES Spogen Biotech Inc. (US) 2020-02-12 EP claimed
CN-109219592-A Benzyl phenylate analog derivative and its preparation method and pharmaceutical composition and purposes 中国医学科学院药物研究所 2019-01-15 CN claimed
WO-2018187345-A1 AGRICULTURAL COMPOSITIONS FOR IMPROVED CROP PRODUCTIVITY AND ENHANCED PHENOTYPES SPOGEN BIOTECH INC. (US) 2018-10-11 WO claimed
CN-107417572-A Benzyl phenylate analog derivative and its preparation method and pharmaceutical composition and purposes 中国医学科学院药物研究所 2017-12-01 CN claimed
US-4374131-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1983-02-15 US claimed
EP-0063896-A1 Amino and substituted amino phosphinyl-alkanoyl compositions E.R. Squibb & Sons, Inc. (US) 1982-11-03 EP claimed
CN-122055379-A Compounds containing one or more diboronate esters and related insulin analogues 普罗托莫科技公司 2026-05-15 CN disclosed
EP-4694932-A2 COMPOUNDS CONTAINING ONE OR MORE DIBORONATES AND RELATED INSULIN ANALOGS Protomer Technologies Inc. (US) 2026-02-18 EP disclosed
EP-4696334-A2 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2026-02-18 EP disclosed
US-12514938-B2 Fibroblast activation protein targeting peptides PERSPECTIVE THERAPEUTICS, INC. (US) 2026-01-06 US disclosed
EP-4619043-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2025-09-24 EP disclosed
US-4416831-A ANGIOTENSIN INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1983-11-22 US disclosed
US-4374131-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1983-02-15 US disclosed
EP-0063896-A1 Amino and substituted amino phosphinyl-alkanoyl compositions E.R. Squibb & Sons, Inc. (US) 1982-11-03 EP disclosed
EP-0052991-A1 Carboxyalkyl amino acid derivatives of various substituted prolines E.R. Squibb & Sons, Inc. (US) 1982-06-02 EP disclosed
US-4316905-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1982-02-23 US disclosed
US-4311705-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1982-01-19 US disclosed